Dissecting the mechanisms of cell division.
cancer
cell cycle
cell division
chemical biology
classical genetics
computational biology
genomics
post-translational modification (PTM)
protein structure
proteomics
Journal
The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R
Informations de publication
Date de publication:
26 07 2019
26 07 2019
Historique:
pubmed:
9
6
2019
medline:
3
4
2020
entrez:
9
6
2019
Statut:
ppublish
Résumé
Cell division is a highly regulated and carefully orchestrated process. Understanding the mechanisms that promote proper cell division is an important step toward unraveling important questions in cell biology and human health. Early studies seeking to dissect the mechanisms of cell division used classical genetics approaches to identify genes involved in mitosis and deployed biochemical approaches to isolate and identify proteins critical for cell division. These studies underscored that post-translational modifications and cyclin-kinase complexes play roles at the heart of the cell division program. Modern approaches for examining the mechanisms of cell division, including the use of high-throughput methods to study the effects of RNAi, cDNA, and chemical libraries, have evolved to encompass a larger biological and chemical space. Here, we outline some of the classical studies that established a foundation for the field and provide an overview of recent approaches that have advanced the study of cell division.
Identifiants
pubmed: 31175154
pii: S0021-9258(20)30643-8
doi: 10.1074/jbc.AW119.008149
pmc: PMC6663871
doi:
Substances chimiques
DNA, Complementary
0
Banques de données
PDB
['5T58']
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
11382-11390Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM117475
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM007185
Pays : United States
Informations de copyright
© 2019 Ong and Torres.
Références
Nucleic Acids Res. 2000 Jan 1;28(1):235-42
pubmed: 10592235
Nature. 1975 Aug 14;256(5518):547-51
pubmed: 1165770
Mol Cell. 2002 Jan;9(1):59-71
pubmed: 11804586
EMBO Rep. 2002 Apr;3(4):341-8
pubmed: 11897663
EMBO J. 2002 May 15;21(10):2496-506
pubmed: 12006501
Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):975-80
pubmed: 12509509
Nat Cell Biol. 2003 Apr;5(4):346-51
pubmed: 12629549
J Cell Biol. 2003 Apr 28;161(2):267-80
pubmed: 12719470
J Biol Chem. 2003 Jul 11;278(28):25277-80
pubmed: 12738781
Dev Cell. 2003 Jun;4(6):813-26
pubmed: 12791267
Mol Biol Cell. 1992 Jan;3(1):73-84
pubmed: 1312880
Nat Struct Mol Biol. 2004 Apr;11(4):338-45
pubmed: 15024386
Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4419-24
pubmed: 15070733
Mol Biol Cell. 2004 Aug;15(8):3841-62
pubmed: 15169868
Exp Cell Res. 2004 Oct 15;300(1):109-20
pubmed: 15383319
Science. 2004 Oct 1;306(5693):117-20
pubmed: 15459393
Mol Biol Cell. 2005 Mar;16(3):1305-18
pubmed: 15616188
Nature. 1979 May 31;279(5712):428-30
pubmed: 16068179
J Neurosci. 2006 Jan 18;26(3):775-84
pubmed: 16421297
J Biol Chem. 1991 Sep 5;266(25):16376-9
pubmed: 1653232
Biophys J. 2006 Jun 1;90(11):3966-82
pubmed: 16533843
Nature. 1991 Sep 12;353(6340):174-7
pubmed: 1653904
Cell. 2006 May 19;125(4):719-32
pubmed: 16713564
Cell. 1991 Mar 22;64(6):1111-22
pubmed: 1706223
Genetics. 1973 Jun;74(2):267-86
pubmed: 17248617
Curr Biol. 2007 Feb 20;17(4):316-22
pubmed: 17291758
Curr Biol. 2007 Feb 20;17(4):304-15
pubmed: 17291761
J Cell Biol. 1991 Feb;112(4):523-33
pubmed: 1825210
Cell. 2008 Feb 8;132(3):487-98
pubmed: 18267078
PLoS Biol. 2008 Mar 4;6(3):e50
pubmed: 18318601
Nature. 1991 Jan 10;349(6305):132-8
pubmed: 1846030
Cell. 2008 Jul 25;134(2):256-67
pubmed: 18662541
Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20215-20
pubmed: 19091947
Nat Cell Biol. 2008 Sep;10(9):1076-82
pubmed: 19160488
Proteomics. 2009 May;9(10):2888-91
pubmed: 19405035
Int J Cancer. 2010 May 1;126(9):2036-48
pubmed: 19739117
Nature. 1991 Jan 10;349(6305):169-72
pubmed: 1986309
Mol Biol Cell. 2010 Mar 15;21(6):897-904
pubmed: 20089842
PLoS Biol. 2010 Jan 26;8(1):e1000287
pubmed: 20126263
J Biol Chem. 1991 Apr 25;266(12):7325-8
pubmed: 2019567
Science. 2010 Apr 30;328(5978):593-9
pubmed: 20360068
Nature. 2010 Apr 1;464(7289):721-7
pubmed: 20360735
J Cell Biol. 2010 Jul 12;190(1):25-34
pubmed: 20624899
Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14633-8
pubmed: 20679239
Cancer Cell. 2010 Oct 19;18(4):382-95
pubmed: 20951947
Cell. 2011 Mar 4;144(5):646-74
pubmed: 21376230
Proc Natl Acad Sci U S A. 1990 Jun;87(12):4766-70
pubmed: 2141171
Nature. 1990 Aug 23;346(6286):760-3
pubmed: 2143810
Mol Cell. 2011 May 20;42(4):511-23
pubmed: 21596315
Cell. 1990 Mar 9;60(5):791-801
pubmed: 2178776
Cell. 1990 May 18;61(4):591-602
pubmed: 2188731
Cell. 2011 Dec 9;147(6):1309-23
pubmed: 22153075
J Cell Biol. 2012 Mar 19;196(6):801-10
pubmed: 22412018
Nature. 2012 Mar 21;484(7393):208-13
pubmed: 22437499
Bioarchitecture. 2012 Jan 1;2(1):19-22
pubmed: 22754624
Nat Struct Mol Biol. 2012 Sep;19(9):925-9
pubmed: 22885327
Cell Death Differ. 2013 Mar;20(3):430-42
pubmed: 23099851
PLoS One. 2012;7(10):e47914
pubmed: 23110129
J Cell Sci. 2013 Feb 1;126(Pt 3):715-21
pubmed: 23264738
Science. 2013 Mar 15;339(6125):1328-1331
pubmed: 23371551
J Biol Chem. 2014 Jan 3;289(1):28-40
pubmed: 24214971
Nat Cell Biol. 2014 Mar;16(3):268-80
pubmed: 24561623
Curr Biol. 2014 Mar 17;24(6):664-70
pubmed: 24613305
EMBO J. 2014 Aug 18;33(16):1815-30
pubmed: 24996901
Nature. 2014 Sep 18;513(7518):388-393
pubmed: 25043029
EMBO J. 1989 Oct;8(10):3053-8
pubmed: 2531073
Cell Death Dis. 2014 Oct 16;5:e1462
pubmed: 25321469
Cell. 1989 Mar 10;56(5):829-38
pubmed: 2538242
Mol Biol Cell. 2015 Feb 1;26(3):440-52
pubmed: 25501367
Chem Biol. 2014 Dec 18;21(12):1707-21
pubmed: 25525990
Mol Oncol. 2015 Jun;9(6):1056-70
pubmed: 25682900
PLoS Genet. 2015 Feb 19;11(2):e1005013
pubmed: 25695507
PLoS Comput Biol. 2015 Mar 31;11(3):e1004153
pubmed: 25826798
Cell Cycle. 2015;14(7):1116-25
pubmed: 25830415
Cell Cycle. 2015;14(12):1938-47
pubmed: 25839665
Protein Sci. 2015 Jul;24(7):1164-72
pubmed: 25970265
Nature. 2015 Jun 25;522(7557):450-454
pubmed: 26083744
Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11252-7
pubmed: 26305957
Nat Commun. 2015 Aug 26;6:8128
pubmed: 26306570
Dev Biol. 2016 Jan 15;409(2):442-50
pubmed: 26658217
Cell Rep. 2016 Jan 12;14(2):180-8
pubmed: 26748699
Nature. 1989 Nov 2;342(6245):39-45
pubmed: 2682257
Nat Commun. 2016 Feb 25;7:10818
pubmed: 26912231
Mol Biol Cell. 2016 Apr 15;27(8):1188-96
pubmed: 26912792
Mol Cell Proteomics. 2016 May;15(5):1658-69
pubmed: 26929214
Sci Rep. 2016 May 10;6:25385
pubmed: 27160062
Cell. 2016 Jun 2;165(6):1440-1453
pubmed: 27259151
ACS Chem Biol. 2016 Aug 19;11(8):2244-53
pubmed: 27285961
Mol Cell. 2016 Aug 18;63(4):593-607
pubmed: 27522463
Mol Cell. 2016 Oct 6;64(1):12-23
pubmed: 27716480
Cell. 2016 Nov 3;167(4):1014-1027.e12
pubmed: 27881300
Mol Cell Biol. 2017 Mar 1;37(6):
pubmed: 28031327
J Vis Exp. 2016 Dec 24;(118):
pubmed: 28060263
Dev Cell. 2017 Feb 27;40(4):405-420.e2
pubmed: 28216383
Br J Cancer. 2017 May 23;116(11):1451-1461
pubmed: 28449010
Nat Commun. 2017 Jun 06;8:15690
pubmed: 28585547
Sci Rep. 2017 Jun 20;7(1):3865
pubmed: 28634351
Sci Rep. 2017 Jul 31;7(1):6862
pubmed: 28761071
Sci Rep. 2017 Sep 12;7(1):11261
pubmed: 28900159
PLoS One. 2017 Dec 11;12(12):e0189324
pubmed: 29228025
Dev Cell. 2018 May 21;45(4):496-511.e6
pubmed: 29787710
Bioinformatics. 2018 Nov 1;34(21):3755-3758
pubmed: 29850778
EMBO J. 2018 Aug 15;37(16):
pubmed: 29973362
J Biol Chem. 2018 Sep 7;293(36):14080-14088
pubmed: 30006350
Nat Commun. 2018 Jul 19;9(1):2834
pubmed: 30026603
Nat Biotechnol. 2018 Oct;36(9):880-887
pubmed: 30125270
Gastroenterology. 2018 Dec;155(6):1951-1966.e26
pubmed: 30165047
Nature. 2018 Sep;561(7723):411-415
pubmed: 30202089
Mol Biol Cell. 2018 Nov 15;29(23):2821-2834
pubmed: 30207830
Cell. 1987 May 22;49(4):559-67
pubmed: 3032459
Mol Biol Cell. 2019 Feb 1;30(3):312-323
pubmed: 30485161
J Cell Biol. 2019 Feb 4;218(2):455-473
pubmed: 30504246
Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):13003-13008
pubmed: 30509972
Elife. 2019 Feb 14;8:null
pubmed: 30762520
Cell Syst. 2019 Feb 27;8(2):163-167.e2
pubmed: 30797774
PLoS Comput Biol. 2019 Feb 27;15(2):e1006678
pubmed: 30811403
ACS Chem Biol. 2019 May 17;14(5):994-1001
pubmed: 31046221
Elife. 2019 May 03;8:null
pubmed: 31050341
Proc Natl Acad Sci U S A. 1988 May;85(9):3009-13
pubmed: 3283736
Cell. 1988 Jul 29;54(3):423-31
pubmed: 3293802
Cell. 1986 Apr 11;45(1):145-53
pubmed: 3955656
J Exp Zool. 1971 Jun;177(2):129-45
pubmed: 5106340
Cell. 1983 Jun;33(2):389-96
pubmed: 6134587
Mol Cell Biol. 1983 Jun;3(6):1000-12
pubmed: 6348512
J Cell Biol. 1984 Apr;98(4):1247-55
pubmed: 6425302
Am J Hum Genet. 1984 Nov;36(6):1332-40
pubmed: 6517054
Gene. 1984 Nov;31(1-3):129-34
pubmed: 6526270
Proc Natl Acad Sci U S A. 1980 Jan;77(1):462-6
pubmed: 6928638
Cell. 1995 Apr 21;81(2):279-88
pubmed: 7736580
Mol Biol Cell. 1995 Feb;6(2):185-97
pubmed: 7787245
J Cell Sci. 1993 Dec;106 ( Pt 4):1153-68
pubmed: 8126097
Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10321-6
pubmed: 8816798
Science. 1998 Feb 13;279(5353):1041-4
pubmed: 9461437
J Cell Sci. 1998 Aug;111 ( Pt 16):2445-53
pubmed: 9683638
Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11324-9
pubmed: 9736735