Health economic evaluation of a web-based intervention for depression: the EVIDENT-trial, a randomized controlled study.

Depression Deprexis E-mental-health Economic issues Health economic evaluation Outcome studies Randomized controlled trial

Journal

Health economics review
ISSN: 2191-1991
Titre abrégé: Health Econ Rev
Pays: Germany
ID NLM: 101583209

Informations de publication

Date de publication:
07 Jun 2019
Historique:
received: 10 12 2018
accepted: 22 05 2019
entrez: 9 6 2019
pubmed: 9 6 2019
medline: 9 6 2019
Statut: epublish

Résumé

Depression often remains undiagnosed or treated inadequately. Web-based interventions for depression may improve accessibility of treatment and reduce disease-related costs. This study aimed to examine the potential of the web-based cognitive behavioral intervention "deprexis" in reducing disease-related costs. Participants with mild to moderate depressive symptoms were recruited and randomized to either a 12-week web-based intervention (deprexis) in addition to care as usual (intervention group) or care as usual (control group). Outcome measures were health-related resource use, use of medication and incapacity to work as well as relating direct health care costs. Outcomes were assessed on patients' self-report at baseline, three months and six months. A total of 1013 participants were randomized. In both groups total direct health care costs decreased during the study period, but changes from baseline did not significantly differ between study groups. Numeric differences between study groups existed in outpatient treatment costs. They could be attributed to differences in changes of costs for psychotherapeutic treatment from baseline. Whereas costs for psychotherapeutic treatment decreased in the intervention group, costs increased in the control group (- 16.8% (€80) vs. + 14.7% (€60)) (t The study indicates the health economic potential of innovative e-mental-health programs. There is evidence to suggest that the use of deprexis over a period of 12 weeks leads to a decrease in outpatient treatment cost, especially in those related to different types of psychotherapeutic treatment.

Sections du résumé

BACKGROUND BACKGROUND
Depression often remains undiagnosed or treated inadequately. Web-based interventions for depression may improve accessibility of treatment and reduce disease-related costs. This study aimed to examine the potential of the web-based cognitive behavioral intervention "deprexis" in reducing disease-related costs.
METHODS METHODS
Participants with mild to moderate depressive symptoms were recruited and randomized to either a 12-week web-based intervention (deprexis) in addition to care as usual (intervention group) or care as usual (control group). Outcome measures were health-related resource use, use of medication and incapacity to work as well as relating direct health care costs. Outcomes were assessed on patients' self-report at baseline, three months and six months.
RESULTS RESULTS
A total of 1013 participants were randomized. In both groups total direct health care costs decreased during the study period, but changes from baseline did not significantly differ between study groups. Numeric differences between study groups existed in outpatient treatment costs. They could be attributed to differences in changes of costs for psychotherapeutic treatment from baseline. Whereas costs for psychotherapeutic treatment decreased in the intervention group, costs increased in the control group (- 16.8% (€80) vs. + 14.7% (€60)) (t
CONCLUSION CONCLUSIONS
The study indicates the health economic potential of innovative e-mental-health programs. There is evidence to suggest that the use of deprexis over a period of 12 weeks leads to a decrease in outpatient treatment cost, especially in those related to different types of psychotherapeutic treatment.

Identifiants

pubmed: 31175475
doi: 10.1186/s13561-019-0233-y
pii: 10.1186/s13561-019-0233-y
pmc: PMC6734272
doi:

Types de publication

Journal Article

Langues

eng

Pagination

16

Subventions

Organisme : Bundesministerium für Gesundheit
ID : II A 5-2512 FSB 052

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Auteurs

Viola Gräfe (V)

Department of Health Economics and Health Care Management, School of Public Health, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany. viola.graefe@uni-bielefeld.de.

Thomas Berger (T)

Department of Clinical Psychology and Psychotherapy, University of Bern, Hochschulstrasse 6, 3012, Bern, Switzerland.

Martin Hautzinger (M)

Department of Psychology, Eberhard Karls University Tuebingen, Schleichstraße 4, 72076, Tuebingen, Germany.

Fritz Hohagen (F)

Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538, Luebeck, Germany.

Wolfgang Lutz (W)

Department of Psychology, University of Trier, Am Wissenschaftspark 25, +2754296, Trier, Germany.

Björn Meyer (B)

Research Department, Gaia AG, Hans-Henny-Jahnn-Weg, 5322085, Hamburg, Germany.

Steffen Moritz (S)

The Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Matthias Rose (M)

Department of Psychosomatic Medicine, Charité University Medical Center, Hindenburgdamm 30, 12200, Berlin, Germany.

Johanna Schröder (J)

The Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.
The Institute for Sex Research and Forensic Psychiatry, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Christina Späth (C)

Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538, Luebeck, Germany.

Jan Philipp Klein (JP)

Department of Psychiatry and Psychotherapy, University of Luebeck, Ratzeburger Allee 160, 23538, Luebeck, Germany.

Wolfgang Greiner (W)

Department of Health Economics and Health Care Management, School of Public Health, Bielefeld University, Universitätsstraße 25, 33615, Bielefeld, Germany.

Classifications MeSH