Electrochemical properties of the interaction between cytochrome c and a hematite nanowire array electrode.


Journal

Bioelectrochemistry (Amsterdam, Netherlands)
ISSN: 1878-562X
Titre abrégé: Bioelectrochemistry
Pays: Netherlands
ID NLM: 100953583

Informations de publication

Date de publication:
Oct 2019
Historique:
received: 31 01 2019
revised: 22 05 2019
accepted: 22 05 2019
pubmed: 9 6 2019
medline: 7 8 2019
entrez: 9 6 2019
Statut: ppublish

Résumé

We investigate the interaction of horse heart cytochrome c (cyt c) with hematite nanowire array electrodes by cyclic voltammetry to study the electron transfer between redox active proteins and mineral surfaces. Using this model system, we quantify electron transfer rates between cyt c and hematite under varying electric potential and pH conditions. The results are consistent with two cyt c conformations adsorbed at the hematite surface: the native and a partially unfolded form. The partially unfolded protein maintained redox activity, but at a lower redox potential than the native protein. Adsorption of cyt c allowed direct electron transfer between cyt c and hematite, with an interfacial electron transfer rate, k°

Identifiants

pubmed: 31176253
pii: S1567-5394(19)30077-5
doi: 10.1016/j.bioelechem.2019.05.012
pii:
doi:

Substances chimiques

Ferric Compounds 0
ferric oxide 1K09F3G675
Cytochromes c 9007-43-6

Types de publication

Journal Article

Langues

eng

Pagination

162-169

Informations de copyright

Copyright © 2019. Published by Elsevier B.V.

Auteurs

Hanyu Wang (H)

Neutron Scattering Division, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831, USA.

Alexander Johs (A)

Environmental Sciences Division, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831, USA.

James F Browning (JF)

Neutron Scattering Division, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831, USA.

David Alan Tennant (DA)

Materials Science and Technology Division, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831, USA.

Liyuan Liang (L)

Environmental Sciences Division, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831, USA. Electronic address: liangl@ornl.gov.

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Classifications MeSH