Nucleoside dimers analogues with a 1,2,3-triazole linkage: conjugation of floxuridine and thymidine provides novel tools for cancer treatment. Part II.
1,3-dipolar cycloaddition
Floxuridine
cancer therapy
nucleoside dimers derivatives
Journal
Nucleosides, nucleotides & nucleic acids
ISSN: 1532-2335
Titre abrégé: Nucleosides Nucleotides Nucleic Acids
Pays: United States
ID NLM: 100892832
Informations de publication
Date de publication:
2019
2019
Historique:
pubmed:
11
6
2019
medline:
30
10
2019
entrez:
11
6
2019
Statut:
ppublish
Résumé
The fluorinated nucleoside dimers with a 1,2,3-triazole linkage are novel compounds within the field of bioorganic chemistry. We report on the synthesis and properties of two groups of nucleoside dimers analogs possessing a different arrangement of the 1,4-disubstituted 1,2,3-triazole linkage. Based on analysis of the
Identifiants
pubmed: 31177919
doi: 10.1080/15257770.2019.1610891
doi:
Substances chimiques
Antineoplastic Agents
0
Nucleosides
0
Triazoles
0
Floxuridine
039LU44I5M
Thymidine
VC2W18DGKR
Types de publication
Journal Article
Video-Audio Media
Langues
eng
Sous-ensembles de citation
IM