Body mass and atrial fibrillation risk: Status of the epidemiology concerning the influence of fat versus lean body mass.


Journal

Trends in cardiovascular medicine
ISSN: 1873-2615
Titre abrégé: Trends Cardiovasc Med
Pays: United States
ID NLM: 9108337

Informations de publication

Date de publication:
05 2020
Historique:
received: 25 02 2019
revised: 20 05 2019
accepted: 27 05 2019
pubmed: 11 6 2019
medline: 22 10 2020
entrez: 11 6 2019
Statut: ppublish

Résumé

Obesity is repeatedly proclaimed an important risk factor for atrial fibrillation (AF) and considered one of the most promising targets for prevention. This widely held view has been questioned by recent findings, which suggest that AF risk is associated with a high lean (aka fat-free) body mass, whereas fat carries little or no independent risk of AF. Focusing on these recent results, the present overview summarizes and interprets the evidence underlying this apparent controversy and discusses whether a change of paradigm is warranted in AF research or in clinical practice. The overall conclusion is that the excess AF risk in obese persons seems primarily associated with other characteristics than the amount of adipose tissue per se.

Identifiants

pubmed: 31178265
pii: S1050-1738(19)30074-X
doi: 10.1016/j.tcm.2019.05.009
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

205-211

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2019 The Author(s). Published by Elsevier Inc. All rights reserved.

Auteurs

Morten Fenger-Grøn (M)

Research Unit for General Practice, Aarhus, Denmark; Department of Public Health, Aarhus University, Denmark. Electronic address: mfgr@ph.au.dk.

Nicklas Vinter (N)

Diagnostic Centre, University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

Lars Frost (L)

Diagnostic Centre, University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, Silkeborg, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

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Classifications MeSH