Microbicidal Phagocytosis of Nucleus Pulposus Cells Against


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2019
Historique:
received: 22 01 2019
accepted: 07 05 2019
entrez: 11 6 2019
pubmed: 11 6 2019
medline: 10 9 2020
Statut: epublish

Résumé

Intervertebral disc (IVD) is an immune-privileged organ that lacks immunocytes, such as macrophages or neutrophils; therefore, it is unclear how IVD immunological defense against bacterial infection occurs. Here, we demonstrated that nucleus pulposus cells (NPCs), the vital machinery for maintaining the homeostasis of IVD, exerted microbicidal activity against

Identifiants

pubmed: 31178866
doi: 10.3389/fimmu.2019.01132
pmc: PMC6538773
doi:

Substances chimiques

Biomarkers 0
TLR2 protein, human 0
Toll-Like Receptor 2 0
Mitogen-Activated Protein Kinases EC 2.7.11.24

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1132

Références

Nature. 2000 Oct 12;407(6805):784-8
pubmed: 11048729
Lancet. 2001 Jun 23;357(9273):2024-5
pubmed: 11438138
Cell Death Differ. 2001 Jul;8(7):734-46
pubmed: 11464218
Cell. 2001 Aug 10;106(3):255-8
pubmed: 11509172
QJM. 2001 Sep;94(9):465-70
pubmed: 11528009
Biochem J. 2002 Sep 15;366(Pt 3):689-704
pubmed: 12061891
Spine (Phila Pa 1976). 2002 Nov 15;27(22):2484-90
pubmed: 12435979
Nat Rev Immunol. 2004 Jul;4(7):499-511
pubmed: 15229469
Cytometry A. 2005 Jun;65(2):93-102
pubmed: 15825183
Immunity. 2005 May;22(5):539-50
pubmed: 15894272
Infect Immun. 2005 Dec;73(12):8397-401
pubmed: 16299338
J Bone Joint Surg Am. 2006 Apr;88 Suppl 2:10-4
pubmed: 16595436
J Immunol. 2006 Sep 15;177(6):4047-54
pubmed: 16951368
J Immunol. 2007 Nov 1;179(9):6160-8
pubmed: 17947691
Cell Res. 2008 Apr;18(4):436-42
pubmed: 18347614
Arthritis Res Ther. 2008;10(4):R86
pubmed: 18673547
Nat Rev Microbiol. 2009 May;7(5):355-66
pubmed: 19369951
Infect Immun. 2010 Jun;78(6):2857-67
pubmed: 20368346
Dis Model Mech. 2011 Jan;4(1):31-41
pubmed: 21123625
Diagn Interv Imaging. 2012 Jun;93(6):520-9
pubmed: 22677300
Front Cell Infect Microbiol. 2013 Jan 04;2:167
pubmed: 23316483
Eur Spine J. 2013 Apr;22(4):690-6
pubmed: 23397187
J Invest Dermatol. 2013 Aug;133(8):2004-12
pubmed: 23446985
Cell Signal. 2014 Apr;26(4):806-14
pubmed: 24412754
PLoS Pathog. 2014 Feb 20;10(2):e1003918
pubmed: 24586149
PLoS One. 2014 Aug 04;9(8):e103411
pubmed: 25089618
J Clin Invest. 2014 Nov;124(11):4926-40
pubmed: 25295542
Immunobiology. 2015 Jan;220(1):10-9
pubmed: 25454489
Eur Spine J. 2015 Nov;24(11):2496-502
pubmed: 26287263
Spine (Phila Pa 1976). 2016 Jun;41(11):935-9
pubmed: 26679882
Spine (Phila Pa 1976). 2016 Dec 15;41(24):1860-1865
pubmed: 27669046
Front Cell Infect Microbiol. 2017 Mar 15;7:78
pubmed: 28361042
PLoS One. 2017 Apr 3;12(4):e0174518
pubmed: 28369127
Biomed Res Int. 2017;2017:6192935
pubmed: 28401158
Emerg Microbes Infect. 2018 Jan 10;7(1):1
pubmed: 29323102
Acta Neurochir (Wien). 2018 Mar;160(3):487-496
pubmed: 29356895
Z Orthop Unfall. 2019 Apr;157(2):132-143
pubmed: 30053761
J Cell Biol. 1994 Mar;124(5):677-88
pubmed: 8120091
Br Med Bull. 1997;53(3):491-508
pubmed: 9374033

Auteurs

Yazhou Lin (Y)

Department of Orthopedics, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.
Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases With Integrated Chinese-Western Medicine, Ruijin Hospital, Shanghai Institute of Traumatology and Orthopedics, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Hui Cong (H)

Department of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, China.

Kewei Liu (K)

Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases With Integrated Chinese-Western Medicine, Ruijin Hospital, Shanghai Institute of Traumatology and Orthopedics, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Yucheng Jiao (Y)

Department of Orthopedics, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.
Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases With Integrated Chinese-Western Medicine, Ruijin Hospital, Shanghai Institute of Traumatology and Orthopedics, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Ye Yuan (Y)

Department of Orthopedics, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.
Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases With Integrated Chinese-Western Medicine, Ruijin Hospital, Shanghai Institute of Traumatology and Orthopedics, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Guoqing Tang (G)

Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.

Yong Chen (Y)

Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.

Yuehuan Zheng (Y)

Department of Orthopedics, Ruijin Hospital North, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Jiaqi Xiao (J)

Department of Medical Microbiology and Parasitology, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Changwei Li (C)

Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases With Integrated Chinese-Western Medicine, Ruijin Hospital, Shanghai Institute of Traumatology and Orthopedics, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Zhe Chen (Z)

Department of Orthopedics, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.
Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases With Integrated Chinese-Western Medicine, Ruijin Hospital, Shanghai Institute of Traumatology and Orthopedics, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Peng Cao (P)

Department of Orthopedics, Kunshan Hospital of Traditional Chinese Medicine, Kunshan, China.
Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases With Integrated Chinese-Western Medicine, Ruijin Hospital, Shanghai Institute of Traumatology and Orthopedics, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH