Lessons Learned from RADIOSOUND-HTN: Different Technologies and Techniques for Catheter-based Renal Denervation and Their Effect on Blood Pressure.
Renal denervation
renal nerves
resistant hypertension
sympathetic nervous system
ultrasound ablation
Journal
Interventional cardiology (London, England)
ISSN: 1756-1485
Titre abrégé: Interv Cardiol
Pays: England
ID NLM: 101559687
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
received:
10
01
2019
accepted:
23
04
2019
entrez:
11
6
2019
pubmed:
11
6
2019
medline:
11
6
2019
Statut:
epublish
Résumé
The interest in renal denervation (RDN) as a treatment for arterial hypertension has returned with three proof of principle trials that have shown recently RDN to be superior to sham treatment. Nevertheless, many questions about this treatment remain open, including those around the optimal interventional technique and technology. To clarify this important question, the authors designed and conducted the Randomized Trial of Different Renal Denervation Devices and Techniques in Patients with Resistant Hypertension (RADIOSOUND-HTN) trial, which compared three RDN treatment arms in a prospective randomised clinical trial. In this article, they comment on the background and results of this trial, and discuss which conclusions can be drawn from the trial, and which questions remain open for future studies in this field.
Identifiants
pubmed: 31178937
doi: 10.15420/icr.2019.03.R1
pmc: PMC6545992
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
102-106Déclaration de conflit d'intérêts
Disclosure: PL received fees as a consultant for ReCor Medical and Medtronic. KF has no conflicts of interest to declare.
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