Structurally Defined α-Tetralol-Based Chiral Hypervalent Iodine Reagents.
Journal
The Journal of organic chemistry
ISSN: 1520-6904
Titre abrégé: J Org Chem
Pays: United States
ID NLM: 2985193R
Informations de publication
Date de publication:
05 Jul 2019
05 Jul 2019
Historique:
pubmed:
11
6
2019
medline:
11
6
2019
entrez:
11
6
2019
Statut:
ppublish
Résumé
A novel class of chiral hypervalent iodine reagents containing an α-tetralol scaffold is introduced. Iodine triacetate is employed in a key step as a highly selective and efficient iodinating reagent for a short and convenient synthesis of iodine(III) derivatives. Solid-state X-ray analyses offer valuable structural information, while reactivities and stereoselectivities are investigated in three model reactions.
Identifiants
pubmed: 31179710
doi: 10.1021/acs.joc.9b01315
doi:
Types de publication
Journal Article
Langues
eng