Evaluating the effectiveness and cost-effectiveness of the Smoking Treatment Optimisation in Pharmacies (STOP) intervention: protocol for a cluster randomised controlled trial.

Behaviour change Cluster randomised controlled trial Community pharmacy Quit rate Recruitment Retention Smoking cessation

Journal

Trials
ISSN: 1745-6215
Titre abrégé: Trials
Pays: England
ID NLM: 101263253

Informations de publication

Date de publication:
10 Jun 2019
Historique:
received: 08 10 2018
accepted: 15 04 2019
entrez: 12 6 2019
pubmed: 12 6 2019
medline: 28 12 2019
Statut: epublish

Résumé

NHS community pharmacies provide effective smoking cessation services; however, there is scope for increasing throughput and improving quit rates. This trial examines whether the Smoking Treatment Optimisation in Pharmacies (STOP) intervention can improve smoker engagement to increase service throughput, retention and quitting. This study is a pragmatic, cluster randomised controlled trial in 60 pharmacies in England and Wales. All workers in intervention pharmacies are offered STOP training while control pharmacies provide usual care. The STOP intervention, based on behavioural and organisational theories, comprises educational sessions for staff and environmental prompts in the pharmacy. Intervention fidelity is assessed by actors visiting pharmacies posing as smokers. The primary outcome is throughput, defined as the number of smokers who join the programme, set a firm quit date and undergo at least one stop smoking treatment session, and is measured using routinely collected data. Secondary outcomes include retention and quit rates at 4 weeks and continuous abstinence at 6 months verified by salivary cotinine. Cost-effectiveness is estimated using quality-adjusted life years and the probability that the intervention is effective at different levels of willingness to pay is calculated. The trial will generate evidence to inform the public health smoking cessation strategy in England and Wales, and may help to shape service commissioning decisions. The STOP intervention model may help inform the undertaking of a range of health behaviour change tasks in community pharmacies. ClinicalTrials.gov, ISRCTN16351033. Retrospectively registered on 21 March 2017.

Sections du résumé

BACKGROUND BACKGROUND
NHS community pharmacies provide effective smoking cessation services; however, there is scope for increasing throughput and improving quit rates. This trial examines whether the Smoking Treatment Optimisation in Pharmacies (STOP) intervention can improve smoker engagement to increase service throughput, retention and quitting.
METHODS METHODS
This study is a pragmatic, cluster randomised controlled trial in 60 pharmacies in England and Wales. All workers in intervention pharmacies are offered STOP training while control pharmacies provide usual care. The STOP intervention, based on behavioural and organisational theories, comprises educational sessions for staff and environmental prompts in the pharmacy. Intervention fidelity is assessed by actors visiting pharmacies posing as smokers. The primary outcome is throughput, defined as the number of smokers who join the programme, set a firm quit date and undergo at least one stop smoking treatment session, and is measured using routinely collected data. Secondary outcomes include retention and quit rates at 4 weeks and continuous abstinence at 6 months verified by salivary cotinine. Cost-effectiveness is estimated using quality-adjusted life years and the probability that the intervention is effective at different levels of willingness to pay is calculated.
DISCUSSION CONCLUSIONS
The trial will generate evidence to inform the public health smoking cessation strategy in England and Wales, and may help to shape service commissioning decisions. The STOP intervention model may help inform the undertaking of a range of health behaviour change tasks in community pharmacies.
TRIAL REGISTRATION BACKGROUND
ClinicalTrials.gov, ISRCTN16351033. Retrospectively registered on 21 March 2017.

Identifiants

pubmed: 31182134
doi: 10.1186/s13063-019-3368-6
pii: 10.1186/s13063-019-3368-6
pmc: PMC6558670
doi:

Types de publication

Clinical Trial Protocol Evaluation Study Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

337

Subventions

Organisme : Department of Health
ID : RP-PG-0609-10181
Pays : United Kingdom
Organisme : Programme Grants for Applied Research
ID : RP-PG-0609-10181

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Auteurs

Ratna Sohanpal (R)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK. r.sohanpal@qmul.ac.uk.

Sandra Jumbe (S)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Wai-Yee James (WY)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Liz Steed (L)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Tammy Yau (T)

California Northstate University, 9700 West Taron Drive, Elk Grove, CA, 95757, USA.

Carol Rivas (C)

Institute of Education, University College London, London, UK.

Vichithranie Madurasinghe (V)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Colin Houlihan (C)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Vlad Berdunisov (V)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Matthew Taylor (M)

York Health Economics Consortium, University of York, York, UK.

Stephanie J C Taylor (SJC)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Chris Griffiths (C)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Sandra Eldridge (S)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

Robert Walton (R)

Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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Classifications MeSH