Light chain lambda myeloma with fatal AL cardiac amyloidosis in a 21-year-old patient: A case report and review.
cardiac involvement
chemotherapy
daratumumab
light chain myeloma
multi‐organ amyloidosis
Journal
Clinical case reports
ISSN: 2050-0904
Titre abrégé: Clin Case Rep
Pays: England
ID NLM: 101620385
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
02
12
2018
revised:
27
03
2019
accepted:
31
03
2019
entrez:
12
6
2019
pubmed:
12
6
2019
medline:
12
6
2019
Statut:
epublish
Résumé
Multi-organ AL amyloidosis is a therapeutic challenge because of light chain deposits severely damaging the function of concerned organs. Cardiac involvement, which leads to concentric hypertrophy of both ventricles, is particularly severe and leads to poor prognosis regardless of combination chemotherapy. This case pinpoints the relevance of combining clinical, histological, and echocardiographic information in the management of this complex and life-threatening disease.
Identifiants
pubmed: 31183088
doi: 10.1002/ccr3.2165
pii: CCR32165
pmc: PMC6552948
doi:
Types de publication
Case Reports
Langues
eng
Pagination
1171-1177Déclaration de conflit d'intérêts
None declared.
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