Primary squamous cell carcinoma of the peristomal skin of gastrostomy in a transplant patient: a first case report.
Gastrostomy tube
everolimus
squamous cell carcinoma (SCC)
transplant patient
Journal
Journal of gastrointestinal oncology
ISSN: 2078-6891
Titre abrégé: J Gastrointest Oncol
Pays: China
ID NLM: 101557751
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
entrez:
12
6
2019
pubmed:
12
6
2019
medline:
12
6
2019
Statut:
ppublish
Résumé
Gastrostomy is commonly used to provide enteral nutrition when patient require a nutrition support due to not enough oral eating. Gastrostomy tube can lead to many complications; squamous cell carcinoma (SCC) is an extremely rare complication of the site of gastrostomy, it was described after several years of enteral nutrition or as part of a metastasis of head and neck tumors. We describe the case of a 60-year-old man heart-liver transplanted for hereditary amyloidosis. He required the setting of a gastrostomy-tube for enteral feeding and developed after only 18 months a SCC on the site of gastrostomy confirmed in the histologic report. The increased risk of SCC in transplant patients is due to immunosuppressive therapies, even though everolimus could reduce this risk. The pose of a gastrostomy is responsible of a chronic cutaneous inflammation, which is another risk factor for SCC. In these immunocompromised patients, gastrostomy or other chronic skin injury requires special monitoring, especially if the wound does not heal.
Identifiants
pubmed: 31183210
doi: 10.21037/jgo.2019.01.05
pii: jgo-10-03-573
pmc: PMC6534712
doi:
Types de publication
Case Reports
Langues
eng
Pagination
573-576Déclaration de conflit d'intérêts
Conflicts of Interest: The authors have no conflicts of interest to declare.
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