CD151 confers metastatic potential to clear cell sarcoma of the soft tissue in animal model.
SMAD3
clear cell sarcoma
cluster of differentiation 151
matrix metalloproteinase-9
xenoplant assay
Journal
Oncology letters
ISSN: 1792-1074
Titre abrégé: Oncol Lett
Pays: Greece
ID NLM: 101531236
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
22
08
2018
accepted:
31
01
2019
entrez:
13
6
2019
pubmed:
13
6
2019
medline:
13
6
2019
Statut:
ppublish
Résumé
Cluster of differentiation 151 (CD151) is a potent therapeutic target for regulating tumor metastasis. In the present study, the role of CD151 in clear cell sarcoma of soft tissue was examined using a xenoplanted tumor model, which had high rates of metastasis. A clear cell sarcoma cell line, HS-MM, which was transplanted to the aponeuroses of the thighs, the most affected sites of human clear cell sarcoma, exhibited robust lymphatic invasion and nodal metastasis in SCID-beige mice. Serial
Identifiants
pubmed: 31186687
doi: 10.3892/ol.2019.10164
pii: OL-0-0-10164
pmc: PMC6507424
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4811-4818Références
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