Immune Reconstitution Inflammatory Syndrome as a Posttransplantation Complication in Primary Immunodeficiency With Disseminated Mycobacterium avium.


Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN: 1537-6591
Titre abrégé: Clin Infect Dis
Pays: United States
ID NLM: 9203213

Informations de publication

Date de publication:
03 02 2020
Historique:
received: 03 04 2019
accepted: 11 06 2019
pubmed: 14 6 2019
medline: 7 1 2021
entrez: 14 6 2019
Statut: ppublish

Résumé

Patients with primary immunodeficiencies undergoing allogeneic hematopoietic cell transplantation (HCT) for difficult-to-control infections can experience immune reconstitution inflammatory syndrome (IRIS) following engraftment. In 3 patients with post-HCT IRIS related to mycobacterial infection, in vitro data demonstrate the emergence of pathogen-specific immune responses and a concomitant rise in plasma inflammatory markers.

Identifiants

pubmed: 31190050
pii: 5514484
doi: 10.1093/cid/ciz507
pmc: PMC7319264
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

676-679

Informations de copyright

Published by Oxford University Press for the Infectious Diseases Society of America 2019.

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Auteurs

Maura Manion (M)

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Dimana Dimitrova (D)

National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

Luxin Pei (L)

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Juan Gea-Banacloche (J)

Mayo Clinic, Phoenix, Arizona.

Adrian Zelazny (A)

Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland.

Andrea Lisco (A)

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Christa Zerbe (C)

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Alexandra F Freeman (AF)

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Steven M Holland (SM)

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Christopher G Kanakry (CG)

National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

Jennifer A Kanakry (JA)

National Cancer Institute, National Institutes of Health, Bethesda, Maryland.

Irini Sereti (I)

National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

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