Medium Perfusion Flow Improves Osteogenic Commitment of Human Stromal Cells.


Journal

Stem cells international
ISSN: 1687-966X
Titre abrégé: Stem Cells Int
Pays: United States
ID NLM: 101535822

Informations de publication

Date de publication:
2019
Historique:
received: 31 10 2018
revised: 04 02 2019
accepted: 01 03 2019
entrez: 14 6 2019
pubmed: 14 6 2019
medline: 14 6 2019
Statut: epublish

Résumé

Dynamic culture protocols have recently emerged as part of (bone) tissue engineering strategies due to their ability to represent a more physiological cell environment in vitro. Here, we described how a perfusion flow induced by a simple bioreactor system improves proliferation and osteogenic commitment of human bone marrow stromal cells. L88/5 cells were cultured in poly(methyl methacrylate) custom-milled communicating well plates, in the presence of an osteogenic cocktail containing 1

Identifiants

pubmed: 31191662
doi: 10.1155/2019/1304194
pmc: PMC6525824
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1304194

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Auteurs

Alice Pasini (A)

Laboratory of Cellular and Molecular Engineering "S. Cavalcanti," Department of Electrical, Electronic, and Information Engineering "G. Marconi" (DEI), Alma Mater Studiorum-University of Bologna, Cesena, Italy.

Joseph Lovecchio (J)

Laboratory of Cellular and Molecular Engineering "S. Cavalcanti," Department of Electrical, Electronic, and Information Engineering "G. Marconi" (DEI), Alma Mater Studiorum-University of Bologna, Cesena, Italy.
Advanced Research Center on Electronic Systems (ARCES), Alma Mater Studiorum-University of Bologna, Bologna, Italy.

Giulia Ferretti (G)

Laboratory of Cellular and Molecular Engineering "S. Cavalcanti," Department of Electrical, Electronic, and Information Engineering "G. Marconi" (DEI), Alma Mater Studiorum-University of Bologna, Cesena, Italy.

Emanuele Giordano (E)

Laboratory of Cellular and Molecular Engineering "S. Cavalcanti," Department of Electrical, Electronic, and Information Engineering "G. Marconi" (DEI), Alma Mater Studiorum-University of Bologna, Cesena, Italy.
Advanced Research Center on Electronic Systems (ARCES), Alma Mater Studiorum-University of Bologna, Bologna, Italy.
BioEngLab, Health Science and Technology, Interdepartmental Center for Industrial Research (HST-CIRI), Alma Mater Studiorum-University of Bologna, Ozzano Emilia, Italy.

Classifications MeSH