Mesenchymal stem cells confer chemoresistance in breast cancer via a CD9 dependent mechanism.

CD9 MSCs chemoresistance cytokine xenograft tumors

Journal

Oncotarget
ISSN: 1949-2553
Titre abrégé: Oncotarget
Pays: United States
ID NLM: 101532965

Informations de publication

Date de publication:
28 May 2019
Historique:
received: 28 03 2019
accepted: 05 05 2019
entrez: 14 6 2019
pubmed: 14 6 2019
medline: 14 6 2019
Statut: epublish

Résumé

The development of chemotherapy drug resistance remains a significant barrier for effective therapy in several cancers including breast cancer. Bone marrow-derived mesenchymal stem cells (BMMSCs) have previously been shown to influence tumor progression and the development of chemoresistance. In the present study, we showed that when GFP labelled BMMSCs and RFP labelled HCC1806 cells are injected together

Identifiants

pubmed: 31191817
doi: 10.18632/oncotarget.26952
pii: 26952
pmc: PMC6544397
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3435-3450

Déclaration de conflit d'intérêts

CONFLICTS OF INTEREST The authors have no competing financial interests.

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Auteurs

Mujib Ullah (M)

Interventional Regenerative Medicine and Imaging Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, CA 94304, USA.

Asma Akbar (A)

Mid-Florida Research and Education Center, Department of Pathology, University of Florida, Apopka, FL 32703, USA.

Nathan Norton Ng (NN)

Interventional Regenerative Medicine and Imaging Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, CA 94304, USA.

Waldo Concepcion (W)

Interventional Regenerative Medicine and Imaging Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, CA 94304, USA.

Avnesh S Thakor (AS)

Interventional Regenerative Medicine and Imaging Laboratory, Stanford University School of Medicine, Department of Radiology, Palo Alto, CA 94304, USA.

Classifications MeSH