Cytokines and the Pathogenesis of Macular Edema in Branch Retinal Vein Occlusion.
Journal
Journal of ophthalmology
ISSN: 2090-004X
Titre abrégé: J Ophthalmol
Pays: United States
ID NLM: 101524199
Informations de publication
Date de publication:
2019
2019
Historique:
received:
22
01
2019
revised:
19
03
2019
accepted:
08
04
2019
entrez:
14
6
2019
pubmed:
14
6
2019
medline:
14
6
2019
Statut:
epublish
Résumé
Branch retinal vein occlusion (BRVO) is a very common retinal vascular problem in patients with lifestyle-related diseases, such as hypertension and arteriosclerosis. In patients with BRVO, development of macular edema is the main cause of visual impairment. BRVO is still a controversial condition in many respects. Over the years, various methods such as laser photocoagulation have been tried to treat macular edema associated with BRVO, but the results were not satisfactory. After vascular endothelial growth factor (VEGF) was found to have an important role in the pathogenesis of macular edema in BRVO patients, treatment of this condition was revolutionized by development of anti-VEGF therapy. Although macular edema improves dramatically following intraocular injection of anti-VEGF agents, repeated recurrence and resistance of edema is a major problem in some BRVO patients. This suggests that factors or cytokines other than VEGF may be associated with inflammation and retinal hypoxia in BRVO and that the pathogenesis of macular edema is complicated. The present review assesses the role of various factors and cytokines in the pathogenesis of macular edema associated with BRVO. We present a mechanism that is not only plausible but should also be useful for developing new therapeutic strategies.
Identifiants
pubmed: 31191997
doi: 10.1155/2019/5185128
pmc: PMC6525954
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
5185128Références
Atherosclerosis. 1999 Mar;143(1):115-23
pubmed: 10208486
J Biol Chem. 1999 Aug 13;274(33):23463-7
pubmed: 10438525
J Biol Chem. 1999 Aug 27;274(35):25130-5
pubmed: 10455194
Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10836-41
pubmed: 10485912
Am J Physiol. 1999 Nov;277(5):L1057-65
pubmed: 10564193
Ophthalmology. 1999 Nov;106(11):2054-62
pubmed: 10571337
J Biol Chem. 2000 Feb 18;275(7):5096-103
pubmed: 10671553
Invest Ophthalmol Vis Sci. 2000 Mar;41(3):877-9
pubmed: 10711707
J Neuroimmunol. 2001 May 1;116(1):62-73
pubmed: 11311331
Acta Ophthalmol Scand. 2001 Oct;79(5):435-40
pubmed: 11594975
Graefes Arch Clin Exp Ophthalmol. 2001 Oct;239(10):729-32
pubmed: 11760031
Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):566-73
pubmed: 11950692
Trends Cardiovasc Med. 2002 Aug;12(6):241-6
pubmed: 12242046
J Cell Physiol. 2002 Nov;193(2):173-9
pubmed: 12384994
Biochem Soc Trans. 2003 Feb;31(Pt 1):20-4
pubmed: 12546646
Biochem Biophys Res Commun. 2003 Feb 7;301(2):371-7
pubmed: 12565870
Blood. 2003 Aug 15;102(4):1515-24
pubmed: 12689930
Invest Ophthalmol Vis Sci. 2003 May;44(5):2155-62
pubmed: 12714656
Lab Invest. 1992 Feb;66(2):200-11
pubmed: 1346541
J Cell Sci. 2003 Nov 15;116(Pt 22):4615-28
pubmed: 14576355
Invest Ophthalmol Vis Sci. 2003 Nov;44(11):4931-5
pubmed: 14578419
Hypertension. 2004 May;43(5):1098-102
pubmed: 15007035
Am J Ophthalmol. 2004 May;137(5):834-41
pubmed: 15126147
Toxicol Sci. 2005 May;85(1):541-50
pubmed: 15689417
Am J Ophthalmol. 2005 Apr;139(4):739-40
pubmed: 15808186
Am J Ophthalmol. 2005 Aug;140(2):256-61
pubmed: 16086947
Graefes Arch Clin Exp Ophthalmol. 2006 Mar;244(3):309-15
pubmed: 16133018
Endocrinology. 1992 Aug;131(2):710-4
pubmed: 1639018
Jpn J Ophthalmol. 2006 Jan-Feb;50(1):25-32
pubmed: 16453184
Blood. 2006 Sep 15;108(6):1849-56
pubmed: 16709927
J Biochem Mol Biol. 2006 Sep 30;39(5):469-78
pubmed: 17002866
J Gen Virol. 2006 Dec;87(Pt 12):3623-30
pubmed: 17098977
Ophthalmology. 2007 May;114(5):835-54
pubmed: 17397923
Ophthalmology. 1991 Dec;98(12):1824-9
pubmed: 1775317
Br J Ophthalmol. 2008 Apr;92(4):518-22
pubmed: 18211942
Acta Ophthalmol. 2009 Sep;87(6):638-42
pubmed: 18631327
Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1025-32
pubmed: 19060280
Br J Ophthalmol. 2009 May;93(5):630-3
pubmed: 19208676
Proc Natl Acad Sci U S A. 1991 Oct 15;88(20):9267-71
pubmed: 1924389
Arch Ophthalmol. 2009 Sep;127(9):1115-28
pubmed: 19752420
Graefes Arch Clin Exp Ophthalmol. 2010 Feb;248(2):155-9
pubmed: 19763601
PLoS One. 2009 Dec 04;4(12):e8158
pubmed: 19997642
Am J Ophthalmol. 2010 Feb;149(2):291-301.e5
pubmed: 20103055
Graefes Arch Clin Exp Ophthalmol. 2010 Oct;248(10):1515-8
pubmed: 20309574
Ophthalmology. 2010 Jun;117(6):1102-1112.e1
pubmed: 20398941
Ophthalmologica. 2011;225(3):150-4
pubmed: 21150231
Invest Ophthalmol Vis Sci. 2011 May 06;52(6):2982-8
pubmed: 21273540
Ophthalmology. 2011 Aug;118(8):1594-602
pubmed: 21684606
Am J Ophthalmol. 2011 Oct;152(4):669-677.e1
pubmed: 21726846
Ophthalmologica. 2012;227(3):146-52
pubmed: 22269605
Ophthalmology. 2012 Apr;119(4):802-9
pubmed: 22301066
Ophthalmology. 2013 Apr;120(4):795-802
pubmed: 23260261
JAMA Ophthalmol. 2013 Feb;131(2):160-5
pubmed: 23411880
Graefes Arch Clin Exp Ophthalmol. 1990;228(3):201-17
pubmed: 2361592
Int J Biol Sci. 2013 Sep 23;9(9):966-79
pubmed: 24155670
Ophthalmology. 2014 Sep;121(9):1783-9
pubmed: 24768239
BMC Ophthalmol. 2014 May 18;14:67
pubmed: 24884703
Invest Ophthalmol Vis Sci. 2014 Jun 03;55(6):3878-85
pubmed: 24894397
Retina. 2015 May;35(5):1016-27
pubmed: 25574785
Ophthalmologica. 2016;235(4):203-7
pubmed: 27003517
Ophthalmology. 2016 Jun;123(6):1332-44
pubmed: 27039022
Br J Ophthalmol. 2017 Feb;101(2):180-185
pubmed: 27073207
Ophthalmic Res. 2016;56(4):207-214
pubmed: 27160159
Ophthalmologica. 2016;236(4):228-234
pubmed: 27832655
Surv Ophthalmol. 1978 May-Jun;22(6):357-76
pubmed: 354066
Ophthalmology. 1980 Feb;87(2):91-8
pubmed: 7189851
Arch Ophthalmol. 1995 Dec;113(12):1538-44
pubmed: 7487623
N Engl J Med. 1994 Dec 1;331(22):1480-7
pubmed: 7526212
Am J Pathol. 1995 May;146(5):1029-39
pubmed: 7538264
J Biol Chem. 1995 May 12;270(19):11463-71
pubmed: 7744784
J Biol Chem. 1995 Jan 13;270(2):933-43
pubmed: 7822333
J Clin Invest. 1994 Apr;93(4):1564-70
pubmed: 8163658
Graefes Arch Clin Exp Ophthalmol. 1995 Nov;233(11):721-6
pubmed: 8566831
J Clin Invest. 1996 Apr 15;97(8):1931-41
pubmed: 8621778
J Biol Chem. 1996 Jul 26;271(30):17629-34
pubmed: 8663424
Annu Rev Immunol. 1996;14:649-83
pubmed: 8717528
Mol Cell Biol. 1996 Aug;16(8):4231-9
pubmed: 8754823
J Clin Invest. 1996 Nov 1;98(9):2018-26
pubmed: 8903320
Circulation. 1997 Oct 7;96(7):2361-7
pubmed: 9337212
Invest Ophthalmol Vis Sci. 1998 Apr;39(5):793-800
pubmed: 9538887
Am J Ophthalmol. 1998 Nov;126(5):683-90
pubmed: 9822232