Rational Combination of Parvovirus H1 With CTLA-4 and PD-1 Checkpoint Inhibitors Dampens the Tumor Induced Immune Silencing.

H-1PV immune cells immunotherapy ipilimumab melanoma nivolumab

Journal

Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867

Informations de publication

Date de publication:
2019
Historique:
received: 21 01 2019
accepted: 07 05 2019
entrez: 14 6 2019
pubmed: 14 6 2019
medline: 14 6 2019
Statut: epublish

Résumé

The recent therapeutic success of immune checkpoint inhibitors in the treatment of advanced melanoma highlights the potential of cancer immunotherapy. Oncolytic virus-based therapies may further improve the outcome of these cancer patients. A human

Identifiants

pubmed: 31192129
doi: 10.3389/fonc.2019.00425
pmc: PMC6546938
doi:

Types de publication

Journal Article

Langues

eng

Pagination

425

Références

Cancer Gene Ther. 2001 Mar;8(3):158-67
pubmed: 11332986
Cancer Gene Ther. 2003 Jun;10(6):477-80
pubmed: 12768193
Blood. 2004 Apr 1;103(7):2677-82
pubmed: 14630824
Methods Mol Med. 2005;109:285-96
pubmed: 15585928
Int J Cancer. 2005 Nov 20;117(4):538-50
pubmed: 15912538
Hum Gene Ther. 2005 Aug;16(8):996-1005
pubmed: 16076257
Mol Cell Biol. 2005 Nov;25(21):9543-53
pubmed: 16227604
Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):16013-8
pubmed: 16247014
Trends Immunol. 2008 Jun;29(6):272-9
pubmed: 18468488
Clin Cancer Res. 2009 Jan 15;15(2):511-9
pubmed: 19147756
Hum Immunol. 2010 Oct;71(10):934-41
pubmed: 20650297
J Immunol. 2010 Sep 1;185(5):2790-9
pubmed: 20686126
BMC Cancer. 2011 Oct 26;11:464
pubmed: 22029859
Lancet Oncol. 2012 Jan;13(1):e32-42
pubmed: 22225723
PLoS One. 2012;7(2):e32197
pubmed: 22359669
Cancer Res. 2012 Jul 1;72(13):3125-30
pubmed: 22721837
Int J Cancer. 2013 Jun 1;132(11):2548-56
pubmed: 23151948
J Transl Med. 2013 May 01;11:108
pubmed: 23634660
Onco Targets Ther. 2013 Aug 20;6:1119-27
pubmed: 23986643
J Virol. 2014 May;88(10):5263-76
pubmed: 24574398
Front Oncol. 2014 May 01;4:92
pubmed: 24822170
Cancer Immunol Res. 2015 Apr;3(4):399-411
pubmed: 25678581
Curr Treat Options Oncol. 2015 Mar;16(3):326
pubmed: 25777572
Cell. 2015 Sep 10;162(6):1242-56
pubmed: 26359984
Mol Oncol. 2015 Dec;9(10):1936-65
pubmed: 26578451
Ann Transl Med. 2015 Oct;3(18):267
pubmed: 26605313
Viruses. 2015 Dec 09;7(12):6506-25
pubmed: 26690204
J Exp Med. 1989 Sep 1;170(3):797-810
pubmed: 2788708
Onco Targets Ther. 2017 May 02;10:2389-2401
pubmed: 28496337
Hum Gene Ther. 2017 Oct;28(10):800-819
pubmed: 28870120
Mol Ther. 2017 Dec 6;25(12):2620-2634
pubmed: 28967558
Cancer Res. 2018 Jan 15;78(2):436-450
pubmed: 29150430
Viruses. 2017 Dec 15;9(12):
pubmed: 29244745
Hum Vaccin Immunother. 2018 Apr 3;14(4):839-846
pubmed: 29420123
J Immunother Cancer. 2018 May 16;6(1):36
pubmed: 29764498
Melanoma Res. 2018 Oct;28(5):371-379
pubmed: 29957656
Int J Cancer. 1993 Sep 9;55(2):237-44
pubmed: 7690346
J Exp Med. 1994 Jul 1;180(1):35-42
pubmed: 8006593
Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5915-9
pubmed: 8650193
Immunity. 1996 Jun;4(6):535-43
pubmed: 8673700
J Exp Med. 1996 Jun 1;183(6):2533-40
pubmed: 8676074
Eur J Immunol. 1997 Dec;27(12):3135-42
pubmed: 9464798

Auteurs

Katrin Goepfert (K)

Department of Medicine I, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Christiane Dinsart (C)

Infection, Inflammation and Cancer Program, Tumor Virology Division (F010), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Jean Rommelaere (J)

Infection, Inflammation and Cancer Program, Tumor Virology Division (F010), German Cancer Research Center (DKFZ), Heidelberg, Germany.

Friedrich Foerster (F)

Department of Medicine I, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Markus Moehler (M)

Department of Medicine I, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Classifications MeSH