Dosimetric comparison of conformal technique (3D) with volumetric modulated arc therapy with respect to doses obtained in the temporal lobe area in patients irradiated for brain meningioma.
Meningioma
Temporal lobe
Volumetric modulated arc therapy
Journal
Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
ISSN: 1507-1367
Titre abrégé: Rep Pract Oncol Radiother
Pays: Poland
ID NLM: 100885761
Informations de publication
Date de publication:
Historique:
received:
11
09
2018
revised:
17
03
2019
accepted:
12
05
2019
entrez:
14
6
2019
pubmed:
14
6
2019
medline:
14
6
2019
Statut:
ppublish
Résumé
The aim of the analysis was to compare doses obtained for temporal lobes in patients being irradiated for meningiomas of the brain using the conformal technique and volumetric modulated arc therapy (VMAT). We try to answer the question whether the application of VMAT would lead to higher doses within temporal lobes. In recent years a significant increase in the detection of meningiomas and effectiveness of treatment has been observed. Hence quality of life should be considered as an important aspect after a treatment course. Treatment plans of 27 patients were evaluated retrospectively. Radiotherapy procedures were carried out from 2007 until 2016 at the Department of Radiation Oncology in Wroclaw, Poland. For individual patients, alternative treatment plans were generated in relation to the ones originally used, wherein from dynamic techniques, volumetric modulated arc therapy was selected for analysis. Evaluated dosimetric parameters for temporal lobes were: mean dose, V10 Gy, V20 Gy, V45 Gy. Statistically significant differences were observed for V45 Gy for both temporal lobes ( Application of VMAT in patients treated for meningioma of the brain is not related to higher doses of radiation in the temporal lobe area, compared with the conformal technique.
Sections du résumé
AIM
OBJECTIVE
The aim of the analysis was to compare doses obtained for temporal lobes in patients being irradiated for meningiomas of the brain using the conformal technique and volumetric modulated arc therapy (VMAT). We try to answer the question whether the application of VMAT would lead to higher doses within temporal lobes.
BACKGROUND
BACKGROUND
In recent years a significant increase in the detection of meningiomas and effectiveness of treatment has been observed. Hence quality of life should be considered as an important aspect after a treatment course.
MATERIALS AND METHODS
METHODS
Treatment plans of 27 patients were evaluated retrospectively. Radiotherapy procedures were carried out from 2007 until 2016 at the Department of Radiation Oncology in Wroclaw, Poland. For individual patients, alternative treatment plans were generated in relation to the ones originally used, wherein from dynamic techniques, volumetric modulated arc therapy was selected for analysis. Evaluated dosimetric parameters for temporal lobes were: mean dose, V10 Gy, V20 Gy, V45 Gy.
RESULTS
RESULTS
Statistically significant differences were observed for V45 Gy for both temporal lobes (
CONCLUSION
CONCLUSIONS
Application of VMAT in patients treated for meningioma of the brain is not related to higher doses of radiation in the temporal lobe area, compared with the conformal technique.
Identifiants
pubmed: 31193916
doi: 10.1016/j.rpor.2019.05.007
pii: S1507-1367(19)30044-6
pmc: PMC6545355
doi:
Types de publication
Journal Article
Langues
eng
Pagination
325-330Références
Int J Radiat Oncol Biol Phys. 2003 May 1;56(1):83-8
pubmed: 12694826
Radiother Oncol. 2004 Apr;71(1):85-90
pubmed: 15066300
Int J Radiat Oncol Biol Phys. 2007 Jul 1;68(3):858-63
pubmed: 17379447
Int J Radiat Oncol Biol Phys. 2010 Mar 15;76(4):1177-84
pubmed: 19560880
Int J Radiat Oncol Biol Phys. 2010 Jan 1;76(1):287-95
pubmed: 19775832
Radiother Oncol. 2009 Dec;93(3):593-6
pubmed: 19897266
Med Dosim. 2011 Autumn;36(3):264-71
pubmed: 20634054
Neuro Oncol. 2010 Nov;12(11):1173-86
pubmed: 20716593
Int J Radiat Oncol Biol Phys. 2011 Aug 1;80(5):1550-8
pubmed: 21543164
Neoplasma. 2011;58(6):507-15
pubmed: 21895404
Neuro Oncol. 2013 Mar;15(3):360-9
pubmed: 23322748
Clin Cancer Res. 2013 May 1;19(9):2294-300
pubmed: 23388505
PLoS One. 2013 Jul 10;8(7):e67488
pubmed: 23874422
BMC Cancer. 2013 Aug 27;13:397
pubmed: 23978128
Radiother Oncol. 2014 Mar;110(3):471-6
pubmed: 24444525
Phys Med. 2014 Jun;30(4):497-502
pubmed: 24613513
J Radiol Prot. 2014 Jun;34(2):325-31
pubmed: 24705154
Radiother Oncol. 2014 Mar;110(3):390-7
pubmed: 24721546
Int J Radiat Oncol Biol Phys. 2016 Apr 1;94(5):1113-20
pubmed: 27026315
J Neurol Neurosurg Psychiatry. 1989 Apr;52(4):488-92
pubmed: 2786925
Neuro Oncol. 2016 Oct 1;18(suppl_5):v1-v75
pubmed: 28475809
Cancer. 1988 Apr 15;61(8):1535-42
pubmed: 3349419
J Neurosurg. 1994 Feb;80(2):195-201
pubmed: 8283256
Int J Radiat Oncol Biol Phys. 1997 Sep 1;39(2):427-36
pubmed: 9308947