Anti-cancer effects of cinnamon: Insights into its apoptosis effects.
Apoptosis
Cancer
Cinnamon
Therapy
Journal
European journal of medicinal chemistry
ISSN: 1768-3254
Titre abrégé: Eur J Med Chem
Pays: France
ID NLM: 0420510
Informations de publication
Date de publication:
15 Sep 2019
15 Sep 2019
Historique:
received:
15
04
2019
revised:
24
05
2019
accepted:
24
05
2019
pubmed:
14
6
2019
medline:
30
8
2019
entrez:
14
6
2019
Statut:
ppublish
Résumé
Cancer is known as a leading cause of death worldwide. In the last two decades, the incidence of cancer has been dramatically increased mostly due to lifestyle changes. The importance of this issue has attracted further attention to discover novel therapies to prevent and treat cancers. According to previous studies, drugs used to treat cancer have shown significant limitations. Therefore, the role of herbal medicines alone or in combination with chemotherapy drugs has been extensively studied in cancer treatment. Cinnamon is a natural component showing a wide range of pharmacological functions including anti-oxidant, anti-microbial and anti-cancer activities. Impaired apoptosis plays critical roles in the initiation and progression of cancer. Increasing evidence indicates that cinnamon, as a therapeutic agent, has anti-cancer effects via affecting numerous apoptosis-related pathways in cancer cells. Here, we highlighted anticancer properties of cinnamon, particularly through targeting apoptosis-related mechanisms.
Identifiants
pubmed: 31195168
pii: S0223-5234(19)30485-4
doi: 10.1016/j.ejmech.2019.05.067
pii:
doi:
Substances chimiques
2'-benzoyloxycinnamaldehyde
0
Antineoplastic Agents
0
Benzoates
0
Plant Extracts
0
Eugenol
3T8H1794QW
Acrolein
7864XYD3JJ
cinnamaldehyde
SR60A3XG0F
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
131-140Informations de copyright
Copyright © 2019 Elsevier Masson SAS. All rights reserved.