Leonurus japonicus (Chinese motherwort), an excellent traditional medicine for obstetrical and gynecological diseases: A comprehensive overview.


Journal

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
ISSN: 1950-6007
Titre abrégé: Biomed Pharmacother
Pays: France
ID NLM: 8213295

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 18 04 2019
revised: 31 05 2019
accepted: 31 05 2019
pubmed: 14 6 2019
medline: 29 1 2020
entrez: 14 6 2019
Statut: ppublish

Résumé

Leonurus japonicus Houtt. is a traditional medicinal herb with significant effects; dating back more than 1800 years, it is widely used in Asia. In traditional Chinese medicine, it is essential in the treatment of menstrual and delivery disorders caused by blood stasis, such as dysmenorrhea, amenorrhea, and postpartum hemorrhage. In the last three decades, many phytochemists, pharmacologists, and doctors have focused on the chemical components, pharmacological activities, and clinical applications of L. japonicus. More than 280 chemical compounds have been isolated from this plant. The effects of most of the terpenoids and alkaloids isolated from the plant have been found to be closely related to the traditional functions of L. japonicus. Owing to its excellent therapeutic effects for obstetrical and gynecological diseases, L. japonicus has been widely used in both ancient and modern times. Nowadays, it has also been developed into a series of Chinese patent medicines in clinics in China. This review summarizes the phytochemistry, pharmacology, and clinical applications of L. japonicus.

Identifiants

pubmed: 31195353
pii: S0753-3322(19)31777-9
doi: 10.1016/j.biopha.2019.109060
pii:
doi:

Substances chimiques

Phytochemicals 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

109060

Informations de copyright

Copyright © 2019 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

Auteurs

Lu-Lin Miao (LL)

State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Qin-Mei Zhou (QM)

State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.

Cheng Peng (C)

State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: pengchengchengdu@126.com.

Zhao-Hua Liu (ZH)

Chengdu No. 1 Pharmaceutical Co. Ltd., Chengdu 610031, China.

Liang Xiong (L)

State Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; Institute of Innovative Medicine Ingredients of Southwest Specialty Medicinal Materials, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address: xiling0505@126.com.

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Classifications MeSH