New perspectives on screening and early detection of endometrial cancer.


Journal

International journal of cancer
ISSN: 1097-0215
Titre abrégé: Int J Cancer
Pays: United States
ID NLM: 0042124

Informations de publication

Date de publication:
15 12 2019
Historique:
received: 15 02 2019
revised: 27 05 2019
accepted: 31 05 2019
pubmed: 15 6 2019
medline: 31 1 2020
entrez: 15 6 2019
Statut: ppublish

Résumé

Due to the anatomical continuity of the uterine cavity with the cervix, genomic exploitation of material from routine Pap smears and other noninvasive sampling methods represent a unique opportunity to detect signs of disease using biological material shed from the upper genital tract. Recent research findings offer a promising perspective in the detection of endometrial cancer, but certain questions need to be addressed in order to accelerate the implementation of novel technologies in a routine screening or clinical setting. We discuss here new perspectives on detection of endometrial cancer using genomic and other biomarkers in minimally invasive sampling methods with a special focus on public health classic screening criteria, highlighting current gaps in knowledge.

Identifiants

pubmed: 31199503
doi: 10.1002/ijc.32514
doi:

Substances chimiques

Biomarkers, Tumor 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

3194-3206

Informations de copyright

© 2019 UICC.

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Auteurs

Laura Costas (L)

Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Jon Frias-Gomez (J)

Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Magdalena Guardiola (M)

Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Yolanda Benavente (Y)

Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.
Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública, CIBERESP), Madrid, Spain.

Marta Pineda (M)

Hereditary Cancer Program, IDIBELL, Catalan Institute of Oncology, Hospitalet de Llobregat, Barcelona, Spain.

Miquel Á Pavón (MÁ)

Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.
Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Madrid, Spain.

José M Martínez (JM)

Department of Gynecology and Obstetrics, Hospital Universitari de Bellvitge, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Maite Climent (M)

Department of Gynecology and Obstetrics, Hospital Universitari de Bellvitge, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Marc Barahona (M)

Department of Gynecology and Obstetrics, Hospital Universitari de Bellvitge, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Júlia Canet (J)

Hereditary Cancer Program, IDIBELL, Catalan Institute of Oncology, Hospitalet de Llobregat, Barcelona, Spain.

Sonia Paytubi (S)

Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Mónica Salinas (M)

Hereditary Cancer Program, IDIBELL, Catalan Institute of Oncology, Hospitalet de Llobregat, Barcelona, Spain.

Luis Palomero (L)

Program Against Cancer Therapeutic Resistance (ProCURE), IDIBELL, Catalan Institute of Oncology, Hospitalet de Llobregat, Barcelona, Spain.

Ilaria Bianchi (I)

ASSIR Delta, Direcció d'Atenció Primària Costa de Ponent, SAP Delta del Llobregat, Barcelona, Spain.

Jaume Reventós (J)

Departament de Ciències Bàsiques, Universitat Internacional de Catalunya, Barcelona, Spain.

Gabriel Capellà (G)

Hereditary Cancer Program, IDIBELL, Catalan Institute of Oncology, Hospitalet de Llobregat, Barcelona, Spain.
Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Madrid, Spain.

Mireia Diaz (M)

Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.
Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Madrid, Spain.

August Vidal (A)

Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Madrid, Spain.
Department of Pathology, Hospital Universitari de Bellvitge, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Josep M Piulats (JM)

Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Madrid, Spain.
Department of Medical Oncology, IDIBELL, Catalan Institute of Cancer, Hospitalet de Llobregat, Barcelona, Spain.

Álvaro Aytés (Á)

Program Against Cancer Therapeutic Resistance (ProCURE), IDIBELL, Catalan Institute of Oncology, Hospitalet de Llobregat, Barcelona, Spain.

Jordi Ponce (J)

Department of Gynecology and Obstetrics, Hospital Universitari de Bellvitge, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Joan Brunet (J)

Hereditary Cancer Program, IDIBELL, Catalan Institute of Oncology, Hospitalet de Llobregat, Barcelona, Spain.
Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Madrid, Spain.
Medical Sciences Department, School of Medicine, University of Girona, Girona, Spain.

Francesc X Bosch (FX)

Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.
Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Madrid, Spain.

Xavier Matias-Guiu (X)

Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Madrid, Spain.
Department of Pathology, Hospital Universitari de Bellvitge, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

Laia Alemany (L)

Cancer Epidemiology Research Programme, Catalan Institute of Oncology, IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.
Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública, CIBERESP), Madrid, Spain.

Silvia de Sanjosé (S)

Consortium for Biomedical Research in Epidemiology and Public Health (CIBER Epidemiología y Salud Pública, CIBERESP), Madrid, Spain.
PATH, Seattle, WA.

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