Overexpression of IL-10 Enhances the Efficacy of Human Umbilical-Cord-Derived Mesenchymal Stromal Cells in
macrophage
mesenchymal stromal cell
phagocytosis
pneumonia
sepsis
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
13 Jun 2019
13 Jun 2019
Historique:
received:
27
05
2019
revised:
06
06
2019
accepted:
09
06
2019
entrez:
16
6
2019
pubmed:
16
6
2019
medline:
16
6
2019
Statut:
epublish
Résumé
Enhancing the immunomodulatory effects of mesenchymal stromal cells (MSCs) may increase their effects in sepsis. We tested the potential for overexpression of Interleukin-10 (IL-10) in human umbilical cord (UC) MSCs to increase MSC efficacy in
Identifiants
pubmed: 31200579
pii: jcm8060847
doi: 10.3390/jcm8060847
pmc: PMC6616885
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Canadian Institites of Health Research
ID : Operating Grant
Organisme : Science Foundation Ireland
ID : 16/FRL/3845
Pays : Ireland
Déclaration de conflit d'intérêts
The authors declare no conflict of interest. Neither Tissue Regeneration Therapeutics nor the funders had any role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.
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