Mechanisms of synovial joint and articular cartilage development.
Animals
Bone Morphogenetic Proteins
/ genetics
Cartilage, Articular
/ cytology
Cell Differentiation
Cell Lineage
/ genetics
Cell Movement
Chondrocytes
/ cytology
Chondrogenesis
/ genetics
Fibroblast Growth Factors
/ genetics
Gene Expression Regulation
Growth Differentiation Factor 5
/ genetics
Hedgehog Proteins
/ genetics
Humans
Joint Capsule
/ cytology
Osteogenesis
/ genetics
Parathyroid Hormone-Related Protein
/ genetics
Transforming Growth Factor beta
/ genetics
Wnt Signaling Pathway
Articular cartilage
Chondrocyte
Interzone
Joint
Journal
Cellular and molecular life sciences : CMLS
ISSN: 1420-9071
Titre abrégé: Cell Mol Life Sci
Pays: Switzerland
ID NLM: 9705402
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
received:
11
04
2019
accepted:
11
06
2019
revised:
30
05
2019
pubmed:
16
6
2019
medline:
17
10
2019
entrez:
16
6
2019
Statut:
ppublish
Résumé
Articular cartilage is formed at the end of epiphyses in the synovial joint cavity and permanently contributes to the smooth movement of synovial joints. Most skeletal elements develop from transient cartilage by a biological process known as endochondral ossification. Accumulating evidence indicates that articular and growth plate cartilage are derived from different cell sources and that different molecules and signaling pathways regulate these two kinds of cartilage. As the first sign of joint development, the interzone emerges at the presumptive joint site within a pre-cartilage tissue. After that, joint cavitation occurs in the center of the interzone, and the cells in the interzone and its surroundings gradually form articular cartilage and the synovial joint. During joint development, the interzone cells continuously migrate out to the epiphyseal cartilage and the surrounding cells influx into the joint region. These complicated phenomena are regulated by various molecules and signaling pathways, including GDF5, Wnt, IHH, PTHrP, BMP, TGF-β, and FGF. Here, we summarize current literature and discuss the molecular mechanisms underlying joint formation and articular development.
Identifiants
pubmed: 31201464
doi: 10.1007/s00018-019-03191-5
pii: 10.1007/s00018-019-03191-5
doi:
Substances chimiques
Bone Morphogenetic Proteins
0
GDF5 protein, human
0
Growth Differentiation Factor 5
0
Hedgehog Proteins
0
IHH protein, human
0
Parathyroid Hormone-Related Protein
0
Transforming Growth Factor beta
0
Fibroblast Growth Factors
62031-54-3
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
3939-3952Références
PLoS Genet. 2015 Jun 19;11(6):e1005214
pubmed: 26091072
Development. 1998 Dec;125(24):4977-88
pubmed: 9811582
Arthritis Rheum. 2011 Nov;63(11):3333-43
pubmed: 21702022
Arthritis Res Ther. 2014 Jan 15;16(1):R11
pubmed: 24428864
J Biol Chem. 2013 Apr 5;288(14):9924-32
pubmed: 23423383
J Histochem Cytochem. 1995 Mar;43(3):263-73
pubmed: 7868856
Curr Top Dev Biol. 2010;90:291-317
pubmed: 20691853
Cell Tissue Res. 1999 Apr;296(1):111-9
pubmed: 10199971
Science. 1998 May 29;280(5368):1455-7
pubmed: 9603738
J Anat. 1994 Jun;184 ( Pt 3):447-56
pubmed: 7928634
Dev Biol. 2010 May 15;341(2):346-59
pubmed: 20206616
Dev Biol. 2005 Aug 15;284(2):311-22
pubmed: 16023633
Lab Invest. 2011 Dec;91(12):1739-52
pubmed: 21968810
Sci Rep. 2015 May 20;5:10290
pubmed: 25992955
Dev Biol. 2007 Apr 15;304(2):825-33
pubmed: 17313942
Development. 2001 Nov;128(22):4523-34
pubmed: 11714677
Cell. 1996 Aug 23;86(4):599-606
pubmed: 8752214
Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10240-5
pubmed: 8816783
Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):1875-80
pubmed: 23319657
Dev Cell. 2002 Sep;3(3):439-49
pubmed: 12361605
Int J Mol Sci. 2014 Apr 28;15(5):7250-65
pubmed: 24786088
Semin Cell Dev Biol. 2017 Feb;62:50-56
pubmed: 27771363
Development. 1999 Mar;126(6):1305-15
pubmed: 10021348
Am J Physiol Cell Physiol. 2011 May;300(5):C1122-38
pubmed: 21248078
Hum Mol Genet. 2007 Sep 15;16(18):2226-32
pubmed: 17616513
Development. 1999 Oct;126(20):4557-68
pubmed: 10498690
PLoS One. 2007 May 16;2(5):e450
pubmed: 17505543
Ann Anat. 2014 Dec;196(6):402-9
pubmed: 25107481
Bone Res. 2016 Apr 26;4:16009
pubmed: 27563484
Dev Dyn. 2010 Oct;239(10):2547-57
pubmed: 20730871
Dev Biol. 2008 Apr 1;316(1):62-73
pubmed: 18295755
Dev Biol. 2015 Apr 1;400(1):132-8
pubmed: 25641697
Hum Mol Genet. 2006 Jun 1;15(11):1783-92
pubmed: 16624844
Clin Genet. 2002 Jun;61(6):454-8
pubmed: 12121354
J Clin Invest. 2005 Sep;115(9):2373-81
pubmed: 16127465
Dev Biol. 2001 Aug 15;236(2):364-86
pubmed: 11476578
Arthritis Rheum. 2009 Mar;60(3):840-7
pubmed: 19248108
Development. 2012 Nov;139(22):4250-60
pubmed: 23034633
Bone. 1999 Apr;24(4):337-47
pubmed: 10221546
Genes Dev. 2014 Jan 15;28(2):127-39
pubmed: 24449269
J Anat. 2008 Nov;213(5):531-8
pubmed: 19014360
J Biol Chem. 2016 Nov 25;291(48):24912-24921
pubmed: 27729453
PLoS Genet. 2009 Nov;5(11):e1000747
pubmed: 19956691
Ann Anat. 2015 Jul;200:105-13
pubmed: 25866917
Development. 2009 Aug;136(16):2825-35
pubmed: 19633173
Nat Commun. 2016 Oct 07;7:12903
pubmed: 27713395
Cell. 2001 Feb 9;104(3):341-51
pubmed: 11239392
FASEB J. 2017 Mar;31(3):1067-1084
pubmed: 27965322
Am J Anat. 1977 Oct;150(2):333-47
pubmed: 920633
J Clin Invest. 2001 Feb;107(3):295-304
pubmed: 11160153
Nat Biotechnol. 2010 Nov;28(11):1187-94
pubmed: 20967028
PLoS One. 2017 May 3;12(5):e0176752
pubmed: 28467498
Genes Dev. 2004 Oct 1;18(19):2404-17
pubmed: 15371327
Development. 2012 Mar;139(6):1198-212
pubmed: 22354840
J Clin Invest. 1997 Jul 15;100(2):321-30
pubmed: 9218508
PLoS One. 2012;7(8):e42553
pubmed: 22905146
Dev Biol. 2005 Oct 1;286(1):149-57
pubmed: 16122729
J Orthop Res. 1999 Jan;17(1):110-20
pubmed: 10073655
Acta Anat (Basel). 1982;113(4):313-24
pubmed: 7180379
Development. 2015 Mar 1;142(5):817-31
pubmed: 25715393
Development. 2018 Jan 17;145(2):
pubmed: 29247144
Expert Opin Emerg Drugs. 2018 Dec;23(4):331-347
pubmed: 30415584
Genes Dev. 2002 Apr 1;16(7):870-9
pubmed: 11937494
Genes Dev. 2002 Apr 1;16(7):859-69
pubmed: 11937493
Development. 2008 Jun;135(11):1947-56
pubmed: 18434416
J Embryol Exp Morphol. 1977 Jun;39:115-27
pubmed: 886251
Arthritis Rheum. 2013 Oct;65(10):2623-33
pubmed: 23839930
Stem Cell Reports. 2015 Mar 10;4(3):404-18
pubmed: 25733017
Cold Spring Harb Perspect Biol. 2013 Jan 01;5(1):a008334
pubmed: 23284041
Dev Dyn. 2006 Mar;235(3):826-34
pubmed: 16425226
Stem Cells Dev. 2013 Jul 1;22(13):1968-76
pubmed: 23388029
Tissue Eng Part A. 2010 Feb;16(2):545-56
pubmed: 19728793
Development. 2000 Feb;127(3):621-30
pubmed: 10631182
Eur Cell Mater. 2006 Nov 17;12:71-80
pubmed: 17115376
Nat Commun. 2019 Mar 29;10(1):1442
pubmed: 30926814
Mol Biol Rep. 2011 Jun;38(5):2879-85
pubmed: 20099082
Osteoarthritis Cartilage. 2005 Jul;13(7):623-31
pubmed: 15896984
Gene Expr Patterns. 2016 Jan;20(1):22-31
pubmed: 26553002
J Clin Invest. 2005 Apr;115(4):900-9
pubmed: 15841179
Stem Cells Dev. 2013 May 1;22(9):1342-59
pubmed: 23231014
J Cell Sci. 2008 May 1;121(Pt 9):1455-65
pubmed: 18397998
Dev Biol. 1999 May 1;209(1):11-27
pubmed: 10208739
Dev Cell. 2017 May 8;41(3):228-241
pubmed: 28486129
Hum Mol Genet. 2001 Mar 1;10(5):457-65
pubmed: 11181569
Development. 2015 Mar 15;142(6):1169-79
pubmed: 25758226
Osteoarthritis Cartilage. 2016 Apr;24(4):740-51
pubmed: 26522700
Sci Transl Med. 2013 Mar 13;5(176):176ra34
pubmed: 23486780
Matrix Biol. 2019 Apr;77:87-100
pubmed: 30193893
Eur Cell Mater. 2005 Jun 20;9:68-84
pubmed: 15968593
J Biol Chem. 2014 Apr 4;289(14):10192-200
pubmed: 24577103
Dev Biol. 1999 Feb 1;206(1):33-45
pubmed: 9918693
Sci Transl Med. 2011 Sep 21;3(101):101ra93
pubmed: 21937758
Development. 2011 Sep;138(17):3593-612
pubmed: 21828089
Development. 2009 Apr;136(7):1093-104
pubmed: 19224984
J Biol Chem. 2007 Feb 9;282(6):3653-63
pubmed: 17158875
Sports Health. 2009 Nov;1(6):461-8
pubmed: 23015907
Nat Genet. 1997 Sep;17(1):18-9
pubmed: 9288091
Development. 2018 Mar 12;145(5):
pubmed: 29467244
Arthritis Rheumatol. 2016 Apr;68(4):868-79
pubmed: 26636652
Nat Genet. 1996 Mar;12(3):315-7
pubmed: 8589725
Arthritis Res Ther. 2009;11(3):R85
pubmed: 19500336
Nat Commun. 2017 May 16;8:15040
pubmed: 28508891
Cells. 2012 Nov 05;1(4):994-1009
pubmed: 24710539
J Bone Miner Res. 2006 Jan;21(1):113-23
pubmed: 16355280
J Musculoskelet Neuronal Interact. 2002 Sep;2(5):448-56
pubmed: 15758413
Biol Cell. 2008 Mar;100(3):167-77
pubmed: 17976036
Cell. 1994 Jul 29;78(2):335-42
pubmed: 7913883
J Cell Biol. 2007 Jun 18;177(6):1105-17
pubmed: 17576802
Sci Signal. 2015 Jul 21;8(386):ra71
pubmed: 26198357
Genes Dev. 1994 Feb 1;8(3):277-89
pubmed: 8314082
J Tissue Eng Regen Med. 2015 Apr;9(4):332-42
pubmed: 23576364
Nat Rev Endocrinol. 2016 Apr;12(4):203-21
pubmed: 26893264
Dev Biol. 2003 Feb 1;254(1):116-30
pubmed: 12606286
Biomater Sci. 2016 May 26;4(5):734-67
pubmed: 26923076
Clin Sports Med. 2017 Jul;36(3):413-425
pubmed: 28577703
J Cell Biochem. 2013 Apr;114(4):735-42
pubmed: 23060229
J Anat. 2000 Nov;197 Pt 4:659-79
pubmed: 11197539
Dev Dyn. 2008 Jan;237(1):18-27
pubmed: 18058912
PLoS One. 2015 May 01;10(5):e0125192
pubmed: 25933137
Stem Cells Int. 2014;2014:125683
pubmed: 25544847
Bone. 2006 Jul;39(1):61-71
pubmed: 16488673
BMC Genomics. 2014 Jan 20;15:48
pubmed: 24443808
J Clin Invest. 2005 Jul;115(7):1734-42
pubmed: 15951842
Exp Mol Pathol. 2010 Feb;88(1):163-70
pubmed: 19818765
J Biol Chem. 2006 Apr 21;281(16):11011-8
pubmed: 16464862
Front Biosci (Schol Ed). 2012 Jan 01;4:251-68
pubmed: 22202058
Arthritis Rheum. 2008 Dec;58(12):3788-97
pubmed: 19035497
Development. 2005 Dec;132(23):5249-60
pubmed: 16284117
Arthritis Rheum. 2007 Jul;56(7):2312-21
pubmed: 17599751
Nat Rev Rheumatol. 2014 Jan;10(1):11-22
pubmed: 24189839
R Soc Open Sci. 2018 Oct 17;5(10):180604
pubmed: 30473817
Osteoarthritis Cartilage. 2016 Jul;24(7):1235-45
pubmed: 26975812
J Biol Chem. 2005 Mar 25;280(12):11749-58
pubmed: 15647286
Development. 2000 Feb;127(3):605-19
pubmed: 10631181
Development. 1996 Dec;122(12):3969-79
pubmed: 9012517
Osteoarthritis Cartilage. 2007 Apr;15(4):468-74
pubmed: 17052922
Nat Genet. 1997 Sep;17(1):58-64
pubmed: 9288098
Development. 2006 Aug;133(15):3039-49
pubmed: 16818445
J Electron Microsc (Tokyo). 2010;59(3):227-36
pubmed: 20356821
Stem Cells Int. 2017;2017:1960965
pubmed: 28607560
Cancer Res. 2003 Oct 1;63(19):6116-20
pubmed: 14559787
Nature. 1994 Apr 14;368(6472):639-43
pubmed: 8145850
Arthritis Rheumatol. 2015 May;67(5):1261-73
pubmed: 25603997
J Histochem Cytochem. 1998 May;46(5):641-51
pubmed: 9562572
Cell Biol Int. 2002;26(8):679-88
pubmed: 12175671
Arthritis Rheum. 2013 Dec;65(12):3107-19
pubmed: 23982761
Genes Dev. 1999 Aug 15;13(16):2072-86
pubmed: 10465785
Biomater Res. 2018 Mar 16;22:9
pubmed: 29568558
Osteoarthritis Cartilage. 2012 Feb;20(2):162-71
pubmed: 22209871
J Bone Miner Res. 2004 Oct;19(10):1678-88
pubmed: 15355563
Dev Biol. 2007 Oct 15;310(2):304-16
pubmed: 17822689
Arthritis Res Ther. 2011 Aug 11;13(4):R130
pubmed: 21835001
Arthritis Rheumatol. 2016 Oct;68(10):2432-43
pubmed: 27159076
J Mol Histol. 2009 Aug;40(4):311-6
pubmed: 19921490
Development. 2006 Sep;133(18):3695-707
pubmed: 16936073
Arthritis Rheum. 2010 Jun;62(6):1666-74
pubmed: 20191580
J Cell Biochem. 2012 Jul;113(7):2532-42
pubmed: 22415882
Matrix Biol. 1999 Oct;18(5):487-97
pubmed: 10601736
Cell Rep. 2016 Jun 21;15(12):2577-87
pubmed: 27292641
J Cell Sci. 2004 Feb 29;117(Pt 6):889-97
pubmed: 14762107
Nat Genet. 1996 Apr;12(4):390-7
pubmed: 8630492
Bone. 2007 Mar;40(3):577-86
pubmed: 17169623
Development. 2016 May 15;143(10):1811-22
pubmed: 27052727
J Clin Invest. 2016 May 2;126(5):1649-63
pubmed: 27018594
Bone. 2015 May;74:37-47
pubmed: 25576671
Dev Biol. 1993 Feb;155(2):423-30
pubmed: 8432397
Matrix Biol. 2014 Oct;39:5-10
pubmed: 25172830
Mod Rheumatol. 2017 May;27(3):489-492
pubmed: 27435056
Am J Pathol. 2013 Mar;182(3):917-27
pubmed: 23274133
Nat Genet. 2007 Apr;39(4):529-33
pubmed: 17384641
Cells Tissues Organs. 2008;188(3):287-98
pubmed: 18354251
Genes Dis. 2015 Mar 1;2(1):76-95
pubmed: 26000333
PLoS One. 2011 Feb 28;6(2):e17526
pubmed: 21386908
Sci Rep. 2016 Apr 04;6:24039
pubmed: 27041063
Dev Biol. 1999 May 15;209(2):239-53
pubmed: 10328918
Development. 2007 Nov;134(21):3917-28
pubmed: 17913788
PLoS One. 2009 Jun 26;4(6):e6067
pubmed: 19557172
PLoS Biol. 2004 Nov;2(11):e355
pubmed: 15492776
Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14420-5
pubmed: 19590010
Dev Biol. 2017 Jun 1;426(1):56-68
pubmed: 28438606
Anat Embryol (Berl). 2001 Jun;203(6):469-79
pubmed: 11453164
Osteoarthritis Cartilage. 2002 Apr;10(4):308-20
pubmed: 11950254
J Clin Invest. 2005 Mar;115(3):622-31
pubmed: 15719068
Biomed Res. 2015;36(3):179-86
pubmed: 26106047
J Clin Invest. 1999 Dec;104(11):1517-25
pubmed: 10587515
Development. 2010 May;137(9):1461-71
pubmed: 20335360
Dev Cell. 2009 May;16(5):734-43
pubmed: 19460349
Clin Orthop Relat Res. 2004 Oct;(427 Suppl):S69-77
pubmed: 15480079
Arch Biochem Biophys. 1994 May 15;311(1):144-52
pubmed: 8185311
Ann N Y Acad Sci. 2007 Nov;1116:100-12
pubmed: 18083924
Dev Dyn. 2017 Apr;246(4):262-274
pubmed: 27859991
Cells Tissues Organs. 2010;192(2):73-84
pubmed: 20185898
J Bone Miner Res. 2002 May;17(5):898-906
pubmed: 12009021
Sci Transl Med. 2018 Feb 14;10(428):
pubmed: 29444976
Science. 1996 Aug 2;273(5275):663-6
pubmed: 8662561
Arthritis Rheumatol. 2015 Nov;67(11):3070-81
pubmed: 26216721
Am J Pathol. 2009 Nov;175(5):1993-2003
pubmed: 19815716
J Cell Biol. 1991 Nov;115(4):1091-105
pubmed: 1955457