Oligostilbenes from the leaves of Gnetum latifolium and their biological potential to inhibit neuroinflammation.
Animals
Cell Survival
/ drug effects
Cells, Cultured
Density Functional Theory
Dose-Response Relationship, Drug
Gnetum
/ chemistry
Inflammation
/ drug therapy
Mice
Molecular Conformation
Nitric Oxide
/ antagonists & inhibitors
Plant Leaves
/ chemistry
Stilbenes
/ chemistry
Structure-Activity Relationship
Anti-neuroinflammatory activities
Gnetaceae
Gnetum latifolium
Oligostilbene
Journal
Phytochemistry
ISSN: 1873-3700
Titre abrégé: Phytochemistry
Pays: England
ID NLM: 0151434
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
05
01
2019
revised:
29
04
2019
accepted:
27
05
2019
pubmed:
16
6
2019
medline:
16
8
2019
entrez:
16
6
2019
Statut:
ppublish
Résumé
Oligostilbenes are polyphenol oligomers derived from resveratrol and are commonly produced by members of the Gnetaceae family, and many researchers have focused on their anti-inflammatory activities. The EtOAc fraction of a Gnetum latifolium extract showed inhibitory activity against neuroinflammation induced by the transfection of Aβ
Identifiants
pubmed: 31202041
pii: S0031-9422(19)30009-3
doi: 10.1016/j.phytochem.2019.05.017
pii:
doi:
Substances chimiques
Stilbenes
0
Nitric Oxide
31C4KY9ESH
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
112044Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.