Resected thymic large cell neuroendocrine carcinoma: A case report and review of the literature.
Large cell neuroendocrine carcinoma
Surgery
Thymic carcinoma
Thymus
Journal
International journal of surgery case reports
ISSN: 2210-2612
Titre abrégé: Int J Surg Case Rep
Pays: Netherlands
ID NLM: 101529872
Informations de publication
Date de publication:
2019
2019
Historique:
received:
15
03
2019
revised:
20
05
2019
accepted:
30
05
2019
pubmed:
17
6
2019
medline:
17
6
2019
entrez:
17
6
2019
Statut:
ppublish
Résumé
Large cell neuroendocrine carcinoma (LCNEC) of the thymus is an extremely rare neoplasm. We report a rare case of LCNEC of the thymus in a 55-year-old woman. Her chest roentgenogram during a routine checkup revealed an abnormal shadow in the mediastinal left upper lung field. Chest computed tomography showed an anterior mediastinal mass measuring 4.8 × 4.0 cm. Positron emission tomography with 18F-fluorodeoxyglucose (FDG) showed high FDG accumulation at the lesion. To obtain a definitive diagnosis and achieve complete resection, a surgery was performed. The postoperative diagnosis was thymic LCNEC; it was classified as a Masaoka stage III tumor due to the invasion of tumor cells into the left lung. Postoperatively, the patient received adjuvant chemotherapy and survived without any signs of recurrence for 30 months after surgery. The detailed clinical features of thymic LCNEC remain unknown because of its rarity. In total, 20 cases of resection for LCNEC, including the present case, have been reported in the English language literature; we have presented a review of these cases and discussed the optimal therapy for this rare and virulent tumor of the thymus.
Identifiants
pubmed: 31202999
pii: S2210-2612(19)30304-9
doi: 10.1016/j.ijscr.2019.05.057
pmc: PMC6580310
pii:
doi:
Types de publication
Journal Article
Langues
eng
Pagination
53-57Informations de copyright
Copyright © 2019 The Authors. Published by Elsevier Ltd.. All rights reserved.
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