Nanosuspension Technology: Recent Patents on Drug Delivery and their Characterizations.
Nanosuspension
bioavailability
dosing frequency
drug moieties
nanosuspension technology
solubility.
Journal
Recent patents on drug delivery & formulation
ISSN: 2212-4039
Titre abrégé: Recent Pat Drug Deliv Formul
Pays: United Arab Emirates
ID NLM: 101462399
Informations de publication
Date de publication:
2019
2019
Historique:
received:
06
03
2019
revised:
19
04
2019
accepted:
20
04
2019
pubmed:
18
6
2019
medline:
20
2
2020
entrez:
18
6
2019
Statut:
ppublish
Résumé
Nanosuspension has arisen as a remunerative, lucrative as well as a potent approach to improve the solubility and bioavailability of poorly aqueous soluble drug entities. Several challenges are still present in this approach which need more research. The prime aim of this review is to identify such challenges that can be rectified in the future. Through this review, we enlighten the recent patents and advancement in nanosuspension technology that utilize the different drug moieties, instruments and characterization parameters. Nanosuspension has been found to possess great potential to rectify the several issues related to poor bioavailability, site-specific drug delivery, dosing frequency, etc. In the past decade, nanosuspension approach has been complementarily utilized to solve the developed grievances, arisen from poorly soluble drugs. But this field still needs more attention to new discoveries. Nanosuspension contributes a crucial role in administering the different drug entities through a variety of routes involving oral, transdermal, ocular, parenteral, pulmonary, etc. with solving the different issues. This review also confirms the significance of nanosuspension in safety, efficacy, and communal as well as the economic expense associated with healthcare.
Sections du résumé
BACKGROUND
BACKGROUND
Nanosuspension has arisen as a remunerative, lucrative as well as a potent approach to improve the solubility and bioavailability of poorly aqueous soluble drug entities. Several challenges are still present in this approach which need more research. The prime aim of this review is to identify such challenges that can be rectified in the future.
METHODS
METHODS
Through this review, we enlighten the recent patents and advancement in nanosuspension technology that utilize the different drug moieties, instruments and characterization parameters.
RESULTS
RESULTS
Nanosuspension has been found to possess great potential to rectify the several issues related to poor bioavailability, site-specific drug delivery, dosing frequency, etc. In the past decade, nanosuspension approach has been complementarily utilized to solve the developed grievances, arisen from poorly soluble drugs. But this field still needs more attention to new discoveries.
CONCLUSION
CONCLUSIONS
Nanosuspension contributes a crucial role in administering the different drug entities through a variety of routes involving oral, transdermal, ocular, parenteral, pulmonary, etc. with solving the different issues. This review also confirms the significance of nanosuspension in safety, efficacy, and communal as well as the economic expense associated with healthcare.
Identifiants
pubmed: 31203813
pii: DDF-EPUB-98816
doi: 10.2174/1872211313666190614151615
pmc: PMC6806604
doi:
Substances chimiques
Pharmaceutical Preparations
0
Suspensions
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
91-104Informations de copyright
Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
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