New insights into sperm with total globozoospermia: Increased fatty acid oxidation and centrin1 alteration.
Centrin1
F-isoprostanes
PPARγ
globozoospermia
phospholipase A
Journal
Systems biology in reproductive medicine
ISSN: 1939-6376
Titre abrégé: Syst Biol Reprod Med
Pays: England
ID NLM: 101464963
Informations de publication
Date de publication:
Oct 2019
Oct 2019
Historique:
pubmed:
18
6
2019
medline:
12
2
2020
entrez:
18
6
2019
Statut:
ppublish
Résumé
Sperm morphology and lipid profile have a relevant role in male fertility. We explore the status of the sperm centriole, essential structure for human fertilization and the role of fatty acid oxidation in globozoospermia, a rare sperm pathology causing infertility. A case of globozoospermia was characterized by light and electron microscopy, sperm immunolocalization was performed for centrin1, 8-iso-PGF
Identifiants
pubmed: 31204846
doi: 10.1080/19396368.2019.1626934
doi:
Substances chimiques
CETN1 protein, human
0
Calcium-Binding Proteins
0
Cell Cycle Proteins
0
Fatty Acids
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM