Revisiting gametocyte biology in malaria parasites.


Journal

FEMS microbiology reviews
ISSN: 1574-6976
Titre abrégé: FEMS Microbiol Rev
Pays: England
ID NLM: 8902526

Informations de publication

Date de publication:
01 07 2019
Historique:
received: 14 12 2018
accepted: 05 04 2019
pubmed: 21 6 2019
medline: 30 7 2019
entrez: 21 6 2019
Statut: ppublish

Résumé

Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito vector. They are present at low levels in blood circulation and significant knowledge gaps exist in their biology. Recent reductions in the global malaria burden have brought the possibility of elimination and eradication, with renewed focus on malaria transmission biology as a basis for interventions. This review discusses recent insights into gametocyte biology in the major human malaria parasite, Plasmodium falciparum and related species.

Identifiants

pubmed: 31220244
pii: 5435454
doi: 10.1093/femsre/fuz010
pmc: PMC6606849
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Pagination

401-414

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 110166/Z/15/Z
Pays : United Kingdom

Commentaires et corrections

Type : ErratumIn

Informations de copyright

© FEMS 2019.

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Auteurs

Priscilla Ngotho (P)

Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, 120 University Road, Glasgow G12 8TA, UK.

Alexandra Blancke Soares (AB)

Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, 120 University Road, Glasgow G12 8TA, UK.

Franziska Hentzschel (F)

Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, 120 University Road, Glasgow G12 8TA, UK.

Fiona Achcar (F)

Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, 120 University Road, Glasgow G12 8TA, UK.

Lucia Bertuccini (L)

Core Facilities, Microscopy Area, Instituto Superiore di Sanita, Via Regina Elena 299, 00161 Rome, Italy.

Matthias Marti (M)

Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, 120 University Road, Glasgow G12 8TA, UK.
Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston 02115, MA, USA.

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