Validation of the Multi-INdependence Dimensions (MIND) questionnaire for prolonged mechanically ventilated subjects.
Adult
Aged
Argentina
Colombia
Critical Illness
/ therapy
Female
Germany
Health Status
Humans
Longitudinal Studies
Male
Middle Aged
Multivariate Analysis
Prospective Studies
Psychometrics
/ instrumentation
Regression Analysis
Reproducibility of Results
Respiration, Artificial
/ methods
Severity of Illness Index
Surveys and Questionnaires
Composite scores
Health status assessment
MIND questionnaire
Prolonged mechanical ventilation
Questionnaire validation
Rehabilitation
Journal
BMC pulmonary medicine
ISSN: 1471-2466
Titre abrégé: BMC Pulm Med
Pays: England
ID NLM: 100968563
Informations de publication
Date de publication:
20 Jun 2019
20 Jun 2019
Historique:
received:
25
09
2018
accepted:
06
06
2019
entrez:
22
6
2019
pubmed:
22
6
2019
medline:
19
12
2019
Statut:
epublish
Résumé
Evaluating severity of illness of patients with prolonged mechanical ventilation (PMV) is important to adopt the best appropriate care management for each individual. Yet, no severity-of-illness scoring system has been specifically designed for this type of patients. The aim of this study was to develop and validate a new instrument, the Multi-INdependence Dimensions (MIND) questionnaire designed to comprehensively measure the severity of illness of patients under PMV. The validation of the MIND questionnaire was performed during a longitudinal observational study conducted with PMV subjects in weaning facilities in three countries (Argentina, Colombia and Germany). The questionnaire validity was tested in 3 stages: 1) Specification of components, with description of item responses, inter-item and Cronbach alpha correlations; 2) Creation of the composite scores; 3) Measurement properties determination including test-retest reliability after 30 days, clinical validity (Medical Research Council (MRC) muscle strength score, Sepsis-related Organ Failure Assessment (SOFA), Glasgow Coma Scale (GCS), Dependence Nursing Scale and EuroQol-5 Dimension evaluated at inclusion), and ability to detect change. A total of 128 subjects participated in the validation study. Eleven component scores and four composite scores were created. MIND scores significantly correlated with MRC muscle strength, SOFA, DNS, GCS and EQ-5D, supporting the validity of the new scores. Intraclass Correlation Coefficient greater than 0.82 were observed for all composite scores, indicating good test-retest reliability. MIND scores were able to detect improvement in subject severity of illness. The MIND questionnaire is a valid and reliable instrument for measuring comprehensively the multiple dimensions characterizing the severity of illness of PMV patients. NCT02255058 .
Sections du résumé
BACKGROUND
BACKGROUND
Evaluating severity of illness of patients with prolonged mechanical ventilation (PMV) is important to adopt the best appropriate care management for each individual. Yet, no severity-of-illness scoring system has been specifically designed for this type of patients. The aim of this study was to develop and validate a new instrument, the Multi-INdependence Dimensions (MIND) questionnaire designed to comprehensively measure the severity of illness of patients under PMV.
METHODS
METHODS
The validation of the MIND questionnaire was performed during a longitudinal observational study conducted with PMV subjects in weaning facilities in three countries (Argentina, Colombia and Germany). The questionnaire validity was tested in 3 stages: 1) Specification of components, with description of item responses, inter-item and Cronbach alpha correlations; 2) Creation of the composite scores; 3) Measurement properties determination including test-retest reliability after 30 days, clinical validity (Medical Research Council (MRC) muscle strength score, Sepsis-related Organ Failure Assessment (SOFA), Glasgow Coma Scale (GCS), Dependence Nursing Scale and EuroQol-5 Dimension evaluated at inclusion), and ability to detect change.
RESULTS
RESULTS
A total of 128 subjects participated in the validation study. Eleven component scores and four composite scores were created. MIND scores significantly correlated with MRC muscle strength, SOFA, DNS, GCS and EQ-5D, supporting the validity of the new scores. Intraclass Correlation Coefficient greater than 0.82 were observed for all composite scores, indicating good test-retest reliability. MIND scores were able to detect improvement in subject severity of illness.
CONCLUSION
CONCLUSIONS
The MIND questionnaire is a valid and reliable instrument for measuring comprehensively the multiple dimensions characterizing the severity of illness of PMV patients.
TRIAL REGISTRATION
BACKGROUND
NCT02255058 .
Identifiants
pubmed: 31221129
doi: 10.1186/s12890-019-0870-2
pii: 10.1186/s12890-019-0870-2
pmc: PMC6585039
doi:
Banques de données
ClinicalTrials.gov
['NCT02255058']
Types de publication
Journal Article
Multicenter Study
Observational Study
Validation Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
109Subventions
Organisme : Linde AG
ID : Not applicable
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