Vitamin D deficiency and its associated risk factors in normal adult population of Birjand, Iran.


Journal

Clinical nutrition ESPEN
ISSN: 2405-4577
Titre abrégé: Clin Nutr ESPEN
Pays: England
ID NLM: 101654592

Informations de publication

Date de publication:
08 2019
Historique:
received: 15 09 2018
revised: 24 03 2019
accepted: 01 04 2019
entrez: 22 6 2019
pubmed: 22 6 2019
medline: 5 8 2020
Statut: ppublish

Résumé

Vitamin D is required for calcium absorption, bone growth, and regulation of the immune system. Geographical location determines the intensity of the solar ultraviolet (UV) light as a significant determinant of vitamin D status in the many studies. This study was conducted to determine the status of vitamin D deficiency and its associated factors in adults of Birjand city, Iran (latitude: 32.87; longitude: 59.22). This descriptive-analytic study was performed by random stratified sampling on 400 subjects over 40 years of age in Birjand, who signed the consent form for participation. Data were collected in winter within one month from eight municipal health centers. Information regarding demographic characteristics, blood pressure, and anthropometric indices were collected, and blood samples were collected to measure 25-hydroxyvitamin D concentration. The mean serum concentration of 25-OHD was 45.4 nmol/L. Twenty-six percent of subjects had vitamin D deficiency, 45.2% had insufficiency, and 28.8% of the subjects were healthy. The results of the multiple logistic regression showed that age (OR: 0.92, 95% CI = 0.89-0.96) and serum calcium concentration (OR: 0.52, 95% CI = 0.28-0.94) had a significant correlation with 25-OHD deficiency. A high percentage of adults in the city of Birjand are suffering from vitamin D deficiency, which implies a need for extensive training and food enrichment programs, promoting healthy lifestyles, and exercise and walking.

Sections du résumé

BACKGROUND
Vitamin D is required for calcium absorption, bone growth, and regulation of the immune system. Geographical location determines the intensity of the solar ultraviolet (UV) light as a significant determinant of vitamin D status in the many studies. This study was conducted to determine the status of vitamin D deficiency and its associated factors in adults of Birjand city, Iran (latitude: 32.87; longitude: 59.22).
METHODS
This descriptive-analytic study was performed by random stratified sampling on 400 subjects over 40 years of age in Birjand, who signed the consent form for participation. Data were collected in winter within one month from eight municipal health centers. Information regarding demographic characteristics, blood pressure, and anthropometric indices were collected, and blood samples were collected to measure 25-hydroxyvitamin D concentration.
RESULTS
The mean serum concentration of 25-OHD was 45.4 nmol/L. Twenty-six percent of subjects had vitamin D deficiency, 45.2% had insufficiency, and 28.8% of the subjects were healthy. The results of the multiple logistic regression showed that age (OR: 0.92, 95% CI = 0.89-0.96) and serum calcium concentration (OR: 0.52, 95% CI = 0.28-0.94) had a significant correlation with 25-OHD deficiency.
CONCLUSION
A high percentage of adults in the city of Birjand are suffering from vitamin D deficiency, which implies a need for extensive training and food enrichment programs, promoting healthy lifestyles, and exercise and walking.

Identifiants

pubmed: 31221275
pii: S2405-4577(18)30470-4
doi: 10.1016/j.clnesp.2019.04.002
pii:
doi:

Substances chimiques

Vitamin D 1406-16-2
25-hydroxyvitamin D A288AR3C9H

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

113-117

Informations de copyright

Copyright © 2019 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved.

Auteurs

Samaneh Nakhaee (S)

Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.

Mohammad Ali Yaghoubi (M)

Metabolic Syndrome Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Asghar Zarban (A)

Department of Clinical Biochemistry, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran.

Alireza Amirabadizadeh (A)

Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran. Electronic address: amirabadiza921@gmail.com.

Vahideh Faghihi (V)

Islamic Azad University, Science and Research Branch, Tehran, Iran.

Seyed Yoosef Javadmoosavi (S)

Student Research Committee, Birjand University of Medical Sciences, Birjand, Iran.

Homeira Ataei (H)

Medical Toxicology and Drug Abuse Research Center (MTDRC), Birjand University of Medical Sciences, Birjand, Iran.

Omid Mehrpour (O)

Rocky Mountain Poison and Drug Center, Denver, CO, USA.

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Classifications MeSH