Brain functional organization and structure in patients with arteriovenous malformations.
Arteriovenous malformations
Brain development
Cortical thickness
Resting state networks
Journal
Neuroradiology
ISSN: 1432-1920
Titre abrégé: Neuroradiology
Pays: Germany
ID NLM: 1302751
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
received:
07
04
2019
accepted:
06
06
2019
pubmed:
22
6
2019
medline:
6
2
2020
entrez:
22
6
2019
Statut:
ppublish
Résumé
Developmental in nature, brain arteriovenous malformations (AVM) have the potential to affect whole brain organization. Here we investigated the impact of AVM on functional and structural brain organization using resting-state functional MRI (rsfMRI) and cortical thickness measures. We investigated brain functional organization and structure using rsfMRI in conjunction with cortical thickness analyses in 23 patients with cerebral arteriovenous malformations (AVMs) and 20 healthy control subjects. Healthy controls showed the expected anti-correlation between activity in the default mode network (DMN) and frontal areas that are part of the attentional control network. By contrast, patients demonstrated a disruption of this anti-correlation. Disruptions to this anti-correlation were even observed in a subgroup of patients with lesions remote from the main nodes of the DMN and were unrelated to differences in perfusion. Functional connectivity differences were accompanied by reduced cortical thickness in frontal attentional areas in patients compared to the controls. These results contribute to the discussion that AVMs affect whole brain networks and not simply the area surrounding the lesion.
Identifiants
pubmed: 31222381
doi: 10.1007/s00234-019-02245-6
pii: 10.1007/s00234-019-02245-6
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1047-1054Subventions
Organisme : Fonds de Recherche du Québec - Santé
ID : 240019
Références
Adv Tech Stand Neurosurg. 1998;24:131-214
pubmed: 10050213
Proc Natl Acad Sci U S A. 2000 Sep 26;97(20):11050-5
pubmed: 10984517
AJNR Am J Neuroradiol. 2000 Sep;21(8):1423-33
pubmed: 11003274
IEEE Trans Med Imaging. 2001 Jan;20(1):70-80
pubmed: 11293693
Lancet. 2002 Mar 9;359(9309):863-73
pubmed: 11897302
Radiology. 2002 Jun;223(3):672-82
pubmed: 12034934
Int J Radiat Oncol Biol Phys. 2002 Dec 1;54(5):1430-7
pubmed: 12459366
Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9673-8
pubmed: 15976020
Neurosurg Focus. 2001 Nov 15;11(5):e1
pubmed: 16466233
Neuroimage. 2006 Jul 1;31(3):968-80
pubmed: 16530430
Nat Neurosci. 2006 Jul;9(7):971-8
pubmed: 16767087
Nat Rev Neurosci. 2007 Sep;8(9):700-11
pubmed: 17704812
Magn Reson Imaging. 2008 Feb;26(2):261-9
pubmed: 17826940
Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):4028-32
pubmed: 18322013
Ann N Y Acad Sci. 2008 Mar;1124:1-38
pubmed: 18400922
Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1279-84
pubmed: 19164577
J Neurol Sci. 2009 Dec 15;287(1-2):126-30
pubmed: 19729171
Magn Reson Imaging. 2010 Oct;28(8):1051-7
pubmed: 20409665
Interv Neuroradiol. 2009 Dec;15(4):456-61
pubmed: 20465886
Neuroimage. 2010 Dec;53(4):1181-96
pubmed: 20637289
Neuropsychopharmacology. 2011 Sep;36(10):2009-17
pubmed: 21654735
Neuroimage. 2012 Jan 16;59(2):1420-8
pubmed: 21889994
Brain Connect. 2012;2(3):125-41
pubmed: 22642651
Interv Neuroradiol. 2013 Sep;19(3):329-38
pubmed: 24070082
Dev Cogn Neurosci. 2014 Oct;10:148-59
pubmed: 25282602
Cortex. 2015 Mar;64:271-80
pubmed: 25562175
J Cereb Blood Flow Metab. 2017 Jul;37(7):2526-2538
pubmed: 27683452
Handb Clin Neurol. 2017;143:25-29
pubmed: 28552148
Netw Neurosci. 2018 Jun 01;2(2):200-217
pubmed: 30215033
J Neurosurg. 1988 Mar;68(3):352-7
pubmed: 3343606
J Neurosurg. 1986 Oct;65(4):476-83
pubmed: 3760956
IEEE Trans Med Imaging. 1998 Feb;17(1):87-97
pubmed: 9617910
Arch Neurol. 1999 Jan;56(1):103-6
pubmed: 9923768
Neuroimage. 1999 Feb;9(2):179-94
pubmed: 9931268