Extra-skeletal manifestations in mice affected by

Diseases Pathogenesis

Journal

Bone research
ISSN: 2095-4700
Titre abrégé: Bone Res
Pays: China
ID NLM: 101608652

Informations de publication

Date de publication:
2019
Historique:
received: 11 09 2018
accepted: 10 05 2019
entrez: 25 6 2019
pubmed: 25 6 2019
medline: 25 6 2019
Statut: epublish

Résumé

Autosomal dominant osteopetrosis type 2 (ADO2) is a high-density brittle bone disease characterized by bone pain, multiple fractures and skeletal-related events, including nerve compression syndrome and hematological failure. We demonstrated that in mice carrying the heterozygous

Identifiants

pubmed: 31231577
doi: 10.1038/s41413-019-0055-x
pii: 55
pmc: PMC6559989
doi:

Types de publication

Journal Article

Langues

eng

Pagination

17

Déclaration de conflit d'intérêts

Competing interestsA.T., N.R., M.C., and A.M. are co-inventors of the patented siRNA treatment for the ADO2 therapy used in this article. The remaining authors declare no competing interests.

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Auteurs

Antonio Maurizi (A)

1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Mattia Capulli (M)

1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Annabel Curle (A)

1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Rajvi Patel (R)

1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Argia Ucci (A)

1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Juliana Alves Côrtes (JA)

1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Harriet Oxford (H)

1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Shireen R Lamandé (SR)

2Murdoch Children's Research Institute and University of Melbourne, Melbourne, Australia.

John F Bateman (JF)

2Murdoch Children's Research Institute and University of Melbourne, Melbourne, Australia.

Nadia Rucci (N)

1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Anna Teti (A)

1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.

Classifications MeSH