The stilbene derivatives, nucleosides, and nucleosides modified by stilbene derivatives.


Journal

Bioorganic chemistry
ISSN: 1090-2120
Titre abrégé: Bioorg Chem
Pays: United States
ID NLM: 1303703

Informations de publication

Date de publication:
09 2019
Historique:
received: 29 01 2019
revised: 23 04 2019
accepted: 15 06 2019
pubmed: 25 6 2019
medline: 21 10 2020
entrez: 25 6 2019
Statut: ppublish

Résumé

In this short review, including 187 references, the issues of biological activity of stilbene derivatives and nucleosides and the biological and medicinal potential of fusion of these two classes are discussed. The stilbenes, especially the stilbenoids, and nucleosides are both biologically active. Hybrids formed from binding of these compounds have not yet been broadly studied. However, those that have been investigated exhibit desirable medicinal properties. The review is divided in such parts: I. Derivative of stilbene (biomedical investigations, biological activities in cells, enzymes and hazard), parts II. naturally occurred nucleoside and its derivatives: uridine, thymidine and 5-methyluridine, cytidine, adenosine, guanosine and part III. hybrid molecules- drugs and hybrid molecules- nucleoside - stilbene and its derivative.

Identifiants

pubmed: 31234131
pii: S0045-2068(19)30142-7
doi: 10.1016/j.bioorg.2019.103073
pii:
doi:

Substances chimiques

Anti-HIV Agents 0
Antineoplastic Agents 0
Antioxidants 0
Nucleosides 0
Stilbenes 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

103073

Informations de copyright

Copyright © 2019. Published by Elsevier Inc.

Auteurs

Hanna Krawczyk (H)

Department of Organic Chemistry, Faculty of Chemistry, Warsaw University of Technology, Noakowskiego 3, 00-664 Warsaw, Poland. Electronic address: hkraw@ch.pw.edu.pl.

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Classifications MeSH