Sex Moderates the Effect of Aerobic Exercise on Some Aspects of Cognition in Cognitively Intact Younger and Middle-Age Adults.

BMI executive function processing speed

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
21 Jun 2019
Historique:
received: 29 04 2019
revised: 17 06 2019
accepted: 18 06 2019
entrez: 26 6 2019
pubmed: 27 6 2019
medline: 27 6 2019
Statut: epublish

Résumé

We recently reported the results of a randomized, parallel-group, observer-masked, community-based clinical trial of 132 cognitively normal individuals aged 20-67 with below median aerobic capacity who were randomly assigned to one of two 6-month, four-times-weekly conditions: aerobic exercise and stretching/toning. We now assessed potential sex moderation on exercise-related changes in aerobic capacity, BMI and cognitive function. There was no sex moderation of the effect of aerobic exercise on aerobic capacity or BMI. We had previously reported an effect of aerobic exercise on executive function that was moderated by age. We found additional moderation by sex, such that in any age range men improved more than women. Processing speed showed significant sex moderation but not significant age moderation. In men, processing speed significantly improved by week 12 (b = 0.35,

Identifiants

pubmed: 31234307
pii: jcm8060886
doi: 10.3390/jcm8060886
pmc: PMC6617072
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NIA NIH HHS
ID : K01 AG051348
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG033546
Pays : United States

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Auteurs

Yaakov Stern (Y)

Department of Neurology and Taub Institute, Cognitive Neuroscience Division, Columbia University, New York, NY 10032, USA. ys11@columbia.edu.

Seonjoo Lee (S)

Mental Health Data Science, New York State Psychiatric Institute, New York, NY 10032, USA. sl3670@cumc.columbia.edu.
Department of Biostatistics, Columbia University, New York, NY 10032, USA. sl3670@cumc.columbia.edu.

David Predovan (D)

Department of Neurology and Taub Institute, Cognitive Neuroscience Division, Columbia University, New York, NY 10032, USA. dp2931@cumc.columbia.edu.

Richard P Sloan (R)

Department of Psychiatry, Division of Behavioral Medicine, Columbia University, New York, NY 10032, USA. rps7@cumc.columbia.edu.

Classifications MeSH