Visceral fat thickness of erosive and non-erosive reflux disease subjects in Indonesia's tertiary referral hospital.
Cross-Sectional Studies
Esophagitis, Peptic
/ epidemiology
Female
Follow-Up Studies
Gastroesophageal Reflux
/ epidemiology
Humans
Incidence
Indonesia
/ epidemiology
Intra-Abdominal Fat
/ physiopathology
Male
Middle Aged
Obesity
/ complications
Prognosis
Risk Factors
Tertiary Care Centers
/ statistics & numerical data
Erosive esophagitis
GERD
Visceral fat thickness
Journal
Diabetes & metabolic syndrome
ISSN: 1878-0334
Titre abrégé: Diabetes Metab Syndr
Pays: Netherlands
ID NLM: 101462250
Informations de publication
Date de publication:
Historique:
received:
19
03
2019
accepted:
16
04
2019
entrez:
26
6
2019
pubmed:
27
6
2019
medline:
19
12
2019
Statut:
ppublish
Résumé
There has been an increasing number of reports regarding the correlation between obesity and gastroesophageal reflux disease (GERD). Visceral fat thickness is thought to be a risk factor for GERD and its severity. Several studies have conflicting results, so this study aimed to determine visceral fat thickness difference between erosive and non-erosive reflux disease. A cross-sectional study of 56 adult subjects with GERD symptoms was held at Cipto Mangunkusumo National General Hospital between April and November 2018. Gastroesophageal Reflux Disease Questionnaires (GERDQ) were utilized to determine the presence of GERD. Ultrasonography was used to determine visceral fat thickness. Esophageal erosions were diagnosed using upper gastrointestinal endoscopy. The difference in visceral fat thickness between esophagitis and non-esophagitis group was analysed using T-test. From 56 total subjects, 55.4% have erosive reflux disease (ERD), in which were dominated by subjects with grade A esophagitis (64.5%) based on Los Angeles Classification of Esophagitis (LA classifications). There was no significant difference of visceral fat thickness between non-erosive reflux disease (NERD) and ERD (p = 0,831). There was, however, an increasing trend of visceral fat thickness with the advancing severity of esophagitis, although statistical significance was not reached. Visceral fat thickness as measured by ultrasonography has no significant difference between NERD and ERD.
Sections du résumé
BACKGROUND
BACKGROUND
There has been an increasing number of reports regarding the correlation between obesity and gastroesophageal reflux disease (GERD). Visceral fat thickness is thought to be a risk factor for GERD and its severity. Several studies have conflicting results, so this study aimed to determine visceral fat thickness difference between erosive and non-erosive reflux disease.
METHODS
METHODS
A cross-sectional study of 56 adult subjects with GERD symptoms was held at Cipto Mangunkusumo National General Hospital between April and November 2018. Gastroesophageal Reflux Disease Questionnaires (GERDQ) were utilized to determine the presence of GERD. Ultrasonography was used to determine visceral fat thickness. Esophageal erosions were diagnosed using upper gastrointestinal endoscopy. The difference in visceral fat thickness between esophagitis and non-esophagitis group was analysed using T-test.
RESULTS
RESULTS
From 56 total subjects, 55.4% have erosive reflux disease (ERD), in which were dominated by subjects with grade A esophagitis (64.5%) based on Los Angeles Classification of Esophagitis (LA classifications). There was no significant difference of visceral fat thickness between non-erosive reflux disease (NERD) and ERD (p = 0,831). There was, however, an increasing trend of visceral fat thickness with the advancing severity of esophagitis, although statistical significance was not reached.
CONCLUSION
CONCLUSIONS
Visceral fat thickness as measured by ultrasonography has no significant difference between NERD and ERD.
Identifiants
pubmed: 31235117
pii: S1871-4021(19)30200-0
doi: 10.1016/j.dsx.2019.04.025
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1929-1933Informations de copyright
Copyright © 2019 Diabetes India. Published by Elsevier Ltd. All rights reserved.