Intramammary Angiomatoid Fibrous Histiocytoma, a Rare


Journal

Case reports in pathology
ISSN: 2090-6781
Titre abrégé: Case Rep Pathol
Pays: United States
ID NLM: 101576609

Informations de publication

Date de publication:
2019
Historique:
received: 04 03 2019
revised: 19 04 2019
accepted: 07 05 2019
entrez: 26 6 2019
pubmed: 27 6 2019
medline: 27 6 2019
Statut: epublish

Résumé

Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor that is most commonly reported to arise in the subcutaneous tissues of the upper extremities in adolescents and young adults. At present, the WHO classifies this neoplasm as a tumor of uncertain differentiation. AFH is most often clinically regarded as a tumor of intermediate risk due to low reported rates of recurrence and only rare occurrences of metastases. Its histomorphological hallmarks are a prominent lymphoid cuff surrounding a spindle cell neoplasm with syncytial-appearing cytoplasm. Several variant morphologies have been described. Genetically, the tumor is characterized by translocations involving the

Identifiants

pubmed: 31236300
doi: 10.1155/2019/9012878
pmc: PMC6545754
doi:

Types de publication

Case Reports

Langues

eng

Pagination

9012878

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Auteurs

F K Bruehl (FK)

RJ Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

K L Cooper (KL)

Department of Pathology, St. Vincent Charity Medical Center, Cleveland, OH, USA.

S E Kilpatrick (SE)

RJ Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

M D Weindel (MD)

RJ Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

M Ganea (M)

RJ Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

C Astbury (C)

RJ Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

E P Downs-Kelly (EP)

RJ Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

C D Sturgis (CD)

RJ Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

Classifications MeSH