Combining Mathematical Models With Experimentation to Drive Novel Mechanistic Insights Into Macrophage Function.
IBD
in silico experimentation
macrophages
mechanistic mathematical models
monocytes
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2019
2019
Historique:
received:
20
12
2018
accepted:
20
05
2019
entrez:
28
6
2019
pubmed:
28
6
2019
medline:
21
10
2020
Statut:
epublish
Résumé
This perspective outlines an approach to improve mechanistic understanding of macrophages in inflammation and tissue homeostasis, with a focus on human inflammatory bowel disease (IBD). The approach integrates wet-lab and
Identifiants
pubmed: 31244837
doi: 10.3389/fimmu.2019.01283
pmc: PMC6563075
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1283Subventions
Organisme : Medical Research Council
Pays : United Kingdom
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