Impact of microaxillar mechanical left ventricular support on renal resistive index in patients with cardiogenic shock after myocardial infarction: a pilot trial to predict renal organ dysfunction in cardiogenic shock.


Journal

European heart journal. Acute cardiovascular care
ISSN: 2048-8734
Titre abrégé: Eur Heart J Acute Cardiovasc Care
Pays: England
ID NLM: 101591369

Informations de publication

Date de publication:
Mar 2020
Historique:
pubmed: 28 6 2019
medline: 28 11 2020
entrez: 28 6 2019
Statut: ppublish

Résumé

To evaluate the effects of left ventricular support with the microaxial left ventricular pump using the Impella device on the renal resistive index assessed by Doppler ultrasonography in haemodynamically stable patients with cardiogenic shock following myocardial infarction. A non-randomised interventional single-centre study. Consecutive patients with cardiogenic shock supported with an Impella were included during May 2018 and October 2018. The renal resistive index determined as a quotient of (peak systolic velocity - end diastolic velocity)/ peak systolic velocity was obtained using Doppler ultrasound; invasive blood pressure was determined in radial artery simultaneously for safety reasons. A total of 15 patients were measured. The renal resistive index was determined in both kidneys in 13 patients and for one kidney in two patients, respectively. The mean difference between right and left renal resistive index was 0.026 ± 0.023 ( Microaxillar mechanical support by the Impella device in haemodynamically stable patients with cardiogenic shock led to a significant reduction of the renal resistive index without affecting systolic or diastolic blood pressure. This observation is consistent with the notion that Impella support may promote renal organ protection by enhancing renal perfusion.

Identifiants

pubmed: 31246097
doi: 10.1177/2048872619860218
pmc: PMC7068781
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

158-163

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Auteurs

Birgit Markus (B)

Department of Cardiology, Angiology and Intensive Care Medicine, Philipps University Marburg, Germany.

Nikolaos Patsalis (N)

Department of Cardiology, Angiology and Intensive Care Medicine, Philipps University Marburg, Germany.

Georgios Chatzis (G)

Department of Cardiology, Angiology and Intensive Care Medicine, Philipps University Marburg, Germany.

Ulrich Luesebrink (U)

Department of Cardiology, Angiology and Intensive Care Medicine, Philipps University Marburg, Germany.

Holger Ahrens (H)

Department of Cardiology, Angiology and Intensive Care Medicine, Philipps University Marburg, Germany.

Bernhard Schieffer (B)

Department of Cardiology, Angiology and Intensive Care Medicine, Philipps University Marburg, Germany.

Konstantinos Karatolios (K)

Department of Cardiology, Angiology and Intensive Care Medicine, Philipps University Marburg, Germany.

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Classifications MeSH