Blue-Enriched White Light Therapy Reduces Fatigue in Survivors of Severe Traumatic Brain Injury: A Randomized Controlled Trial.


Journal

The Journal of head trauma rehabilitation
ISSN: 1550-509X
Titre abrégé: J Head Trauma Rehabil
Pays: United States
ID NLM: 8702552

Informations de publication

Date de publication:
Historique:
pubmed: 28 6 2019
medline: 10 9 2021
entrez: 28 6 2019
Statut: ppublish

Résumé

Fatigue is one of the disabling sequelae of traumatic brain injury (TBI), with repercussions on quality of life, rehabilitation, and professional reintegration. Research is needed on effective interventions. We evaluated efficacy of blue-enriched white light (BWL) therapy on fatigue of patients with severe TBI. Physical Medicine and Rehabilitation and Physiology departments of University hospitals. Adult patients with fatigue symptoms following severe TBI, Fatigue Severity Scale (FSS) score 4 or more, Epworth Sleepiness Scale (ESS) score 10 or more, and/or Pittsburgh Sleep Quality Index (PSQI]) more than 5 were randomly assigned to one of 2 parallel groups: a BWL therapy group, with 30-minute exposure to waking white light enriched with blue for 4 weeks, and a group without light therapy (N-BWL), no light. Randomized controlled trial. ClinicalTrials.gov number: NCT02420275. The primary outcome measure was the response of the FSS to 4 weeks of treatment. In addition, we assessed latency change of the P300 component of event-related potentials before and after therapy. Significant improvement in the FSS score (P = .026) was found in the BWL group compared with the N-BWL group. BWL phototherapy reduces fatigue in patients with severe TBI.

Identifiants

pubmed: 31246878
doi: 10.1097/HTR.0000000000000500
pii: 00001199-202003000-00010
doi:

Banques de données

ClinicalTrials.gov
['NCT02420275']

Types de publication

Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

E78-E85

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Auteurs

Maria-Antonia Quera Salva (MA)

Sleep and Clinical Neurophysiology Units, Department of Physiology (Drs Quera Salva, Azabou, Hartley, Sauvagnac, and Leotard), INSERM CIC1429 (Ms Vaugier and Dr Barbot), Department of Physical Medicine and Rehabilitation (Drs Vallat-Azouvi and Azouvi), Laboratory of Psychopathology and Neuropsychology, EA 2027, University Paris 8, Saint-Denis and Antenne UEROS-UGECAMIF (Dr Vallat-Azouvi), Raymond-Poincaré Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Garches, France; EA 4047 HANDIReSP, University of Versailles Saint Quentin (UVSQ), Garches, France (Drs Quera Salva, Azabou, Hartley, Sauvagnac, Leotard, and Azouvi); Department of Physical Medicine and Rehabilitation, Groupe Hospitalier Pitié-Salpêtrière, AP-HP, Paris, France (Dr Pradat Diehl); and Université Pierre et Marie Curie, Paris, France (Dr Pradat Diehl).

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