Changes in tumor vascularity depicted by contrast-enhanced EUS as a predictor of prognosis and treatment efficacy in patients with unresectable pancreatic cancer (PEACE): A study protocol.
Contrast-enhanced endoscopic
endoscopic ultrasound
pancreatic cancer
prognosis
ultrasound
Journal
Endoscopic ultrasound
ISSN: 2303-9027
Titre abrégé: Endosc Ultrasound
Pays: China
ID NLM: 101622292
Informations de publication
Date de publication:
Historique:
pubmed:
30
6
2019
medline:
30
6
2019
entrez:
29
6
2019
Statut:
ppublish
Résumé
Patients with unresectable pancreatic cancer have a poor prognosis. The analysis of prognostic factors before treatment may be helpful in determining the best therapeutic strategies. The aim of the PEACE study is to assess the vascularity of pancreatic malignant tumors using contrast-enhanced harmonic EUS (CEH-EUS) and to clarify the prognostic value of tumor vascularity in patients with locally advanced and metastatic pancreatic cancer. Hereby, we present the protocol of a prospective, nonrandomized, single-arm, multicenter study aiming to assess changes in tumor vascularity using CEH-EUS before and 2 months after treatment initiation in patients with unresectable, locally advanced/metastatic pancreatic cancer and to examine the correlation between vascular changes and treatment response, progression-free survival, and overall survival.
Identifiants
pubmed: 31249159
pii: 260850
doi: 10.4103/eus.eus_16_19
pmc: PMC6714481
doi:
Types de publication
Journal Article
Langues
eng
Pagination
235-240Subventions
Organisme : Medical Research Council
ID : G0801588
Pays : United Kingdom
Organisme : Department of Health
ID : PB-PG-0712-28114
Pays : United Kingdom
Organisme : Pancreatic Cancer UK
ID : RG2014_01_PERERIA
Pays : United Kingdom
Déclaration de conflit d'intérêts
None
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