Uterine artery and umbilical vein blood flow are unaffected by moderate habitual physical activity during pregnancy.


Journal

Prenatal diagnosis
ISSN: 1097-0223
Titre abrégé: Prenat Diagn
Pays: England
ID NLM: 8106540

Informations de publication

Date de publication:
10 2019
Historique:
received: 09 05 2019
revised: 10 06 2019
accepted: 13 06 2019
pubmed: 30 6 2019
medline: 7 7 2020
entrez: 30 6 2019
Statut: ppublish

Résumé

This study aims to noninvasively quantify blood flow in the uterine arteries (UTAs) and umbilical vein (UV) using phase-contrast magnetic resonance imaging (PC-MRI) and test whether these correlate with maternal fitness parameters. Resting UTA and UV flows were measured in 23 healthy 30 ± 3-year-old women who engaged in moderate-intensity physical activity during pregnancy. Participant fitness was characterized in the second and third trimesters using the submaximal oxygen uptake (VO Blood flows in the UTA (957 ± 241 mL/min) and UV (132 ± 38 mL/min/kg) were successfully measured in 20 (87%) participants. Neither was associated with any physical fitness parameters (HR, VO PC-MRI can be used to noninvasively measure blood flow in the UTA and UV. Neither resting UTA nor UV flow is associated with maternal fitness parameters. This is the first MRI-based study to provide novel hemodynamic data suggesting decoupling between maternal moderate fitness level and the maternal-placental-fetal hemodynamic system in healthy, normal body mass index (BMI) pregnancies.

Identifiants

pubmed: 31254464
doi: 10.1002/pd.5517
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

976-985

Subventions

Organisme : CIHR
ID : FDN-143262
Pays : Canada

Informations de copyright

© 2019 John Wiley & Sons, Ltd.

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Auteurs

Dafna Sussman (D)

Translational Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Kinesiology and Physical Education, University of Toronto, Toronto, Ontario, Canada.

Brahmdeep S Saini (BS)

Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.

Jane E Schneiderman (JE)

Kinesiology and Physical Education, University of Toronto, Toronto, Ontario, Canada.
Clinical Research Services, Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada.

Rachel Spitzer (R)

Department of Obstetrics and Gynecology, Mount Sinai Hospital, Toronto, Ontario, Canada.
Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

Mike Seed (M)

Department of Obstetrics and Gynecology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.
Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada.

Stephen J Lye (SJ)

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

Greg D Wells (GD)

Translational Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
Kinesiology and Physical Education, University of Toronto, Toronto, Ontario, Canada.

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