Copper isotopes as possible neoplasia biomarkers in captive wild felids.
cancer
copper
felids
isotopes fractionation
wildlife
Journal
Zoo biology
ISSN: 1098-2361
Titre abrégé: Zoo Biol
Pays: United States
ID NLM: 8807837
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
30
05
2018
revised:
30
04
2019
accepted:
31
05
2019
pubmed:
2
7
2019
medline:
20
8
2019
entrez:
2
7
2019
Statut:
ppublish
Résumé
The longevity of zoo animals is increasing due to continuous improvement in husbandry and veterinary medicine. However, increasing age is correlated to a higher prevalence of neoplasia. Despite tremendous improvement in diagnoses and monitoring capacities, cancers are still a challenge for veterinarians within the global zoo community. The recent use of copper isotopes as biomarkers for neoplasia in both human and veterinary medicine is a promising and cost-effective diagnostic tool. Two hundred and twenty-nine serum samples from 10 different species of wild felids under human care were processed through mass spectrometry to determine the ratio of heavy and light copper isotopes (
Substances chimiques
Biomarkers, Tumor
0
Copper
789U1901C5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
371-383Subventions
Organisme : ISTerre
Organisme : Ecole Normale Supérieure de Lyon
Organisme : inter-Instituts of CNRS
Organisme : Labex Institute of the Origins
Informations de copyright
© 2019 Wiley Periodicals, Inc.