The Massachusetts Hepatitis C Testing Cascade, 2014-2016.

hepatitis C surveillance testing cascade

Journal

Microbiology insights
ISSN: 1178-6361
Titre abrégé: Microbiol Insights
Pays: United States
ID NLM: 101622216

Informations de publication

Date de publication:
2019
Historique:
received: 22 05 2019
accepted: 23 05 2019
entrez: 2 7 2019
pubmed: 2 7 2019
medline: 2 7 2019
Statut: epublish

Résumé

To characterize hepatitis C testing in Massachusetts and guide stakeholders in addressing the needs of people living with hepatitis C. All persons with a positive laboratory report for anti-hepatitis C virus (HCV) antibody, between 2014 and 2016, were included in the testing cascade. Outcomes were HCV tests received after a positive anti-HCV antibody test: nucleic acid test or genotype test. Logistic regression analyses were performed to determine factors associated with progression through the HCV testing cascade. Among those reported anti-HCV antibody positive, a total of 13 194 (61%) cases had a subsequent RNA-based test, and 79% (10 374/13 194) were confirmed with current, active HCV infection. For confirmed HCV cases, 44% (4557/10 374) had a genotype identified. The median time from an antibody-positive test to a RNA-based test was 29 days (interquartile range [IQR] = 7-151). Differences in moving through the testing cascade were observed by birth cohort and race/ethnicity. Improved surveillance capture of demographic information is needed to help public health agencies ensure equity in HCV diagnosis and linkage to care.

Identifiants

pubmed: 31258329
doi: 10.1177/1178636119857961
pii: 10.1177_1178636119857961
pmc: PMC6589943
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1178636119857961

Déclaration de conflit d'intérêts

Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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Auteurs

Quynh T Vo (QT)

Bureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, USA.

Shauna Onofrey (S)

Bureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, USA.

Daniel Church (D)

Bureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, USA.

Kevin Cranston (K)

Bureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, USA.

Alfred DeMaria (A)

Bureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, USA.

R Monina Klevens (RM)

Bureau of Infectious Disease and Laboratory Sciences, Massachusetts Department of Public Health, Boston, MA, USA.

Classifications MeSH