The Impact of Stage and Molecular Subtypes on Survival Outcomes in Young Women with Breast Cancer.


Journal

Journal of adolescent and young adult oncology
ISSN: 2156-535X
Titre abrégé: J Adolesc Young Adult Oncol
Pays: United States
ID NLM: 101543508

Informations de publication

Date de publication:
10 2019
Historique:
pubmed: 2 7 2019
medline: 23 6 2020
entrez: 2 7 2019
Statut: ppublish

Résumé

Young women form a unique cohort in breast cancer, with evidence suggesting a later stage at presentation with more aggressive cancers. We aimed at evaluating the prognostic significance of young age and the impact of stage and molecular subtypes on survival. We conducted an audit of a prospectively maintained database at our institute between 2010 and 2014. All women with available receptor status and documented follow-up were included. The young breast cancer (YBC) cohort comprised 103 women and 230 women constituted the comparator arm (45-55 years). The median follow-up was 4 years. The YBC had a higher incidence of hormone negative tumors (61.1% vs. 46.3%,

Identifiants

pubmed: 31259658
doi: 10.1089/jayao.2019.0023
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

628-634

Auteurs

Nisha Hariharan (N)

Department of Surgical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

T Subramanyeshwar Rao (TS)

Department of Surgical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

Chandra K Naidu (CK)

Department of Surgical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

K V V N Raju (KVVN)

Department of Surgical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

Senthil Rajappa (S)

Department of Medical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

Santa Ayyagari (S)

Department of Medical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

M V T Krishnamohan (MVT)

Department of Medical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

Sudha Murthy (S)

Department of Pathology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

Aparna Suryadevara (A)

Department of Radiation Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

Naren Boleneni (N)

Department of Surgical Oncology, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, India.

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Classifications MeSH