Development and Validation of the Warfarin-Aspirin Bleeding Assessment Tool (WA-BAT) in Children.


Journal

Journal of pediatric hematology/oncology
ISSN: 1536-3678
Titre abrégé: J Pediatr Hematol Oncol
Pays: United States
ID NLM: 9505928

Informations de publication

Date de publication:
08 2020
Historique:
pubmed: 2 7 2019
medline: 1 1 2021
entrez: 2 7 2019
Statut: ppublish

Résumé

Bleeding assessment tools (BATs) aim to screen and estimate bleeding risk in patients with inherited bleeding disorders. However, the use of BAT as a standardized measure for comparing bleeding in patients on long-term thromboprophylaxis has not yet been validated. We developed a self-administrable BAT to assess bleeding in patients undergoing long-term thromboprophylaxis with aspirin or warfarin. Eligible participants were invited to complete the warfarin-aspirin -BAT (WA-BAT) online. The WA-BAT was readministered a number of weeks later to determine intrarater reliability. The WA-BAT showed substantial intrarater reliability and assesses major and minor bleeding associated with long-term warfarin or aspirin use.

Identifiants

pubmed: 31259820
doi: 10.1097/MPH.0000000000001540
pii: 00043426-202008000-00038
doi:

Substances chimiques

Anticoagulants 0
Warfarin 5Q7ZVV76EI
Aspirin R16CO5Y76E

Types de publication

Journal Article Validation Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

e513-e514

Références

Rydz N, James PD. The evolution and value of bleeding assessment tools. J Thromb Haemost. 2012;10:2223–2229.
Monagle P, Chan AKC, Goldenberg NA, et al. Antithrombotic therapy in neonates and children. Chest. 2012;141:e737S–e801S.
Tosetto A, Rodeghiero F, Castaman G, et al. A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM-1 VWD). J Thromb Haemost. 2006;4:766–773.
Harris PA, Taylor R, Thielke R, et al. Research electronic data capture (REDCap)—a metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42:377–381.
Polit DF, Beck CTZuccarini M, Cunningham B. Measurement and Data Quality. Essentials of Nursing Research, 7th ed. Philadelphia, PA: Wolters Kluwer Health/Lippincott Williams & Wilkins; 2010.
Monagle P, Cochrane A, Roberts R, et al. A multicenter, randomized trial comparing heparin/warfarin and acetylsalicylic acid as primary thromboprophylaxis for 2 years after the fontan procedure in children. J Am Coll Cardiol. 2011;58:645–651.
Deforest M, Grabell J, Albert S, et al. Generation and optimization of the self-administered bleeding assessment tool and its validation as a screening test for von Willebrand disease. Haemophilia. 2015;21:e384–e388.

Auteurs

Chantal Attard (C)

Murdoch Children's Research Institute.
Royal Children's Hospital.
Department of Paediatrics, The University of Melbourne, Parkville.

Joanna Huang (J)

Murdoch Children's Research Institute.
Royal Children's Hospital.
School of Clinical Sciences, Monash University, Clayton, Vic., Australia.

Fiona Newall (F)

Murdoch Children's Research Institute.
Royal Children's Hospital.
Department of Paediatrics, The University of Melbourne, Parkville.

Paul Monagle (P)

Murdoch Children's Research Institute.
Royal Children's Hospital.
Department of Paediatrics, The University of Melbourne, Parkville.

Yves d'Udekem (Y)

Murdoch Children's Research Institute.
Royal Children's Hospital.
Department of Paediatrics, The University of Melbourne, Parkville.

Vera Ignjatovic (V)

Murdoch Children's Research Institute.
Royal Children's Hospital.

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