Dark Antibacterial Activity of Rose Bengal.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
29 Jun 2019
Historique:
received: 20 05 2019
revised: 27 06 2019
accepted: 28 06 2019
entrez: 3 7 2019
pubmed: 3 7 2019
medline: 4 12 2019
Statut: epublish

Résumé

The global spread of bacterial resistance to antibiotics promotes a search for alternative approaches to eradication of pathogenic bacteria. One alternative is using photosensitizers for inhibition of Gram-positive and Gram-negative bacteria under illumination. Due to low penetration of visible light into tissues, applications of photosensitizers are currently limited to treatment of superficial local infections. Excitation of photosensitizers in the dark can be applied to overcome this problem. In the present work, dark antibacterial activity of the photosensitizer Rose Bengal alone and in combination with antibiotics was studied. The minimum inhibitory concentrations (MIC) value of Rose Bengal against

Identifiants

pubmed: 31261890
pii: ijms20133196
doi: 10.3390/ijms20133196
pmc: PMC6651402
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Photosensitizing Agents 0
Rose Bengal 1ZPG1ELY14
Silicon Z4152N8IUI

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Faina Nakonechny (F)

Department of Chemical Engineering, Biotechnology and Materials, Ariel University, Ariel 4070000, Israel.

Margarita Barel (M)

Department of Chemical Engineering, Biotechnology and Materials, Ariel University, Ariel 4070000, Israel.

Arad David (A)

Department of Chemical Engineering, Biotechnology and Materials, Ariel University, Ariel 4070000, Israel.

Simor Koretz (S)

Department of Chemical Engineering, Biotechnology and Materials, Ariel University, Ariel 4070000, Israel.

Boris Litvak (B)

Department of Electrical and Electronics Engineering, Ariel University, Ariel 4070000, Israel.

Elena Ragozin (E)

Department of Chemical Sciences, Ariel University, Ariel 4070000, Israel.

Ariel Etinger (A)

Department of Electrical and Electronics Engineering, Ariel University, Ariel 4070000, Israel.

Oz Livne (O)

Department of Electrical and Electronics Engineering, Ariel University, Ariel 4070000, Israel.

Yosef Pinhasi (Y)

Department of Electrical and Electronics Engineering, Ariel University, Ariel 4070000, Israel.

Gary Gellerman (G)

Department of Chemical Sciences, Ariel University, Ariel 4070000, Israel.

Marina Nisnevitch (M)

Department of Chemical Engineering, Biotechnology and Materials, Ariel University, Ariel 4070000, Israel. marinan@ariel.ac.il.

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Classifications MeSH