Autoantibodies to Apolipoprotein A-1 as Independent Predictors of Cardiovascular Mortality in Renal Transplant Recipients.

HDL function anti-apolipoprotein A-1 antibodies biomarker cholesterol prognosis renal transplant recipient

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
29 Jun 2019
Historique:
received: 16 05 2019
revised: 24 06 2019
accepted: 27 06 2019
entrez: 3 7 2019
pubmed: 3 7 2019
medline: 3 7 2019
Statut: epublish

Résumé

Renal transplant recipients (RTRs) are known to have a high cardio-vascular disease (CVD) burden only partly explained by traditional CVD risk factors. The aim of this paper was therefore to determine: i) the prognostic value of autoantibodies against apoA-1 (anti-apoA-1 IgG) for incidence of CVD mortality, all-cause mortality and graft failure in RTR. Four hundred and sixty two (462) prospectively included RTRs were followed for 7.0 years. Baseline anti-apoA-1 IgG were determined and associations with incidence of CVD mortality (

Identifiants

pubmed: 31261925
pii: jcm8070948
doi: 10.3390/jcm8070948
pmc: PMC6679113
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Josephine L C Anderson (JLC)

Department of Pediatrics, University Medical Center Groningen, University of Groningen, 1205 Groningen, The Netherlands.

Sabrina Pagano (S)

Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospital, 1205 Geneva, Switzerland.
Department of Medical Specialties, Faculty of Medicine, Geneva University, 1205 Geneva, Switzerland.

Julien Virzi (J)

Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospital, 1205 Geneva, Switzerland.
Department of Medical Specialties, Faculty of Medicine, Geneva University, 1205 Geneva, Switzerland.

Robin P F Dullaart (RPF)

Department of Endocrinology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.

Wijtske Annema (W)

Department of Pediatrics, University Medical Center Groningen, University of Groningen, 1205 Groningen, The Netherlands.
Institute of Clinical Chemistry, University Hospital of Zurich and University of Zurich, 8006 Zurich, Switzerland.

Folkert Kuipers (F)

Department of Pediatrics, University Medical Center Groningen, University of Groningen, 1205 Groningen, The Netherlands.
Laboratory Medicine, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.

Stephan J L Bakker (SJL)

Department of Nephrology, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.

Nicolas Vuilleumier (N)

Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospital, 1205 Geneva, Switzerland.

Uwe J F Tietge (UJF)

Department of Pediatrics, University Medical Center Groningen, University of Groningen, 1205 Groningen, The Netherlands. uwe.tietge@ki.se.
Division of Clinical Chemistry, Department of Laboratory Medicine H5, Karolinska Institutet, 14183 Stockholm, Sweden. uwe.tietge@ki.se.
Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital, SE-141 86 Stockholm, Sweden. uwe.tietge@ki.se.

Classifications MeSH