Circulating microRNAs as possible biomarkers for coronary artery disease: a narrative review.

circulating coronary artery disease microRNA

Journal

EJIFCC
ISSN: 1650-3414
Titre abrégé: EJIFCC
Pays: Italy
ID NLM: 101092742

Informations de publication

Date de publication:
Jun 2019
Historique:
entrez: 3 7 2019
pubmed: 3 7 2019
medline: 3 7 2019
Statut: epublish

Résumé

Coronary artery disease is one of the most common cardiovascular diseases in the world. Involvement of microRNAs on the pathogenesis of this disease was reported either in beneficial or detrimental way. Different studies have also speculated that circulating microRNAs can be applied as promising biomarkers for the diagnosis of coronary artery disease. Particularly, microRNA-133a seems to fulfill the criteria of ideal biomarkers due to its role in the diagnosis, severity assessment and in prognosis. The panel of circulating microRNAs has also improved the predictive power of coronary artery disease compared to single microRNAs. In this review, the role of circulating microRNAs for early detection, severity assessment and prognosis of coronary artery disease were reviewed.

Identifiants

pubmed: 31263392
pmc: PMC6599194

Types de publication

Journal Article Review

Langues

eng

Pagination

179-194

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Auteurs

Tadele Melak (T)

Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Northwest Ethiopia, Ethiopia.

Habtamu Wondifraw Baynes (HW)

Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Northwest Ethiopia, Ethiopia.

Classifications MeSH