Diagnosing adenomyosis with MRI: a prospective study revisiting the junctional zone thickness cutoff of 12 mm as a diagnostic marker.


Journal

European radiology
ISSN: 1432-1084
Titre abrégé: Eur Radiol
Pays: Germany
ID NLM: 9114774

Informations de publication

Date de publication:
Dec 2019
Historique:
received: 12 10 2018
accepted: 05 06 2019
revised: 05 05 2019
pubmed: 3 7 2019
medline: 6 2 2020
entrez: 3 7 2019
Statut: ppublish

Résumé

To assess the diagnostic accuracy of a junctional zone (JZ) thickness of ≥ 12 mm and morphological features of the JZ in MRI in diagnosing adenomyosis in a premenopausal study population. This single-center, prospective observational study consecutively enrolled 93 premenopausal women suffering from a benign gynecological condition, from September 2014 to August 2016. Institutional review board approval and written consent were obtained. All participants underwent MRI and hysterectomy with a histopathological examination. MR images were evaluated in a blinded fashion by two independent readers. The maximum junctional zone thickness (JZ Adenomyosis was histopathologically confirmed in 57 (61%) of the women. JZ JZ • Measuring the junctional zone thickness is of limited value for diagnosing adenomyosis with MRI and should not be used for diagnosing adenomyosis in premenopausal women with moderate disease severity. • An irregular appearance of the junctional zone, the presence of myometrial cysts, and adenomyoma appear to provide the highest specificity for diagnosing adenomyosis. • A consensus for the definition and reading of the junctional zone is needed.

Identifiants

pubmed: 31264010
doi: 10.1007/s00330-019-06308-3
pii: 10.1007/s00330-019-06308-3
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

6971-6981

Subventions

Organisme : Norske Kvinners Sanitetsforening
ID : NKS14901

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Auteurs

Tina Tellum (T)

Department of Gynecology, Oslo University Hospital, PB 4950, Nydalen, N-0424, Oslo, Norway. tina.tellum@gmail.com.
Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway. tina.tellum@gmail.com.
Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway. tina.tellum@gmail.com.

Gordana V Matic (GV)

Department of Gynecology, Oslo University Hospital, PB 4950, Nydalen, N-0424, Oslo, Norway.
Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.

Johann B Dormagen (JB)

Department of Gynecology, Oslo University Hospital, PB 4950, Nydalen, N-0424, Oslo, Norway.
Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.

Staale Nygaard (S)

Department of Informatics, The Faculty of Mathematics and Natural Sciences, University of Oslo, Oslo, Norway.

Ellen Viktil (E)

Department of Gynecology, Oslo University Hospital, PB 4950, Nydalen, N-0424, Oslo, Norway.
Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.

Erik Qvigstad (E)

Department of Gynecology, Oslo University Hospital, PB 4950, Nydalen, N-0424, Oslo, Norway.
Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.

Marit Lieng (M)

Department of Gynecology, Oslo University Hospital, PB 4950, Nydalen, N-0424, Oslo, Norway.
Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.

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