Hybrid PET/MRI in major cancers: a scoping review.


Journal

European journal of nuclear medicine and molecular imaging
ISSN: 1619-7089
Titre abrégé: Eur J Nucl Med Mol Imaging
Pays: Germany
ID NLM: 101140988

Informations de publication

Date de publication:
Sep 2019
Historique:
received: 27 03 2019
accepted: 13 06 2019
pubmed: 4 7 2019
medline: 15 9 2020
entrez: 4 7 2019
Statut: ppublish

Résumé

PET/MRI was introduced for clinical use in 2011 and is now an established modality for the imaging of brain and certain pelvic cancers, whereas clinical use for the imaging of other forms of cancer is not yet widespread. We therefore systematically investigated what has been published on the use of PET/MRI compared to PET/CT in the imaging of cancers outside the brain, focusing on clinical areas of application related to diagnosis, staging and restaging. A systematic search of PubMed/MEDLINE, Embase and the Cochrane Library was performed. Studies evaluating the diagnostic performance of simultaneous PET/MRI in cancer patients were chosen. A total of 3,138 publications were identified and 116 published during the period 2012-2018 were included and were grouped according to the major cancer forms: 13 head and neck (HNC), 9 breast (BC), 21 prostate (PC), 14 gynaecological, 13 gastrointestinal (GIC), and 46 various cancers. Data from studies comparing PET/MRI and PET/CT for staging/restaging suggested the superiority of The scoping review methodology resulted in the identification of a huge number of records, of which less than 5% were suitable for inclusion and only a limited number allowed conclusions on the advantages/disadvantages of PET/MRI compared to PET/CT in the oncological setting. There was evidence to support the use of FDG PET/MRI in staging of nasopharyngeal cancer and high-risk BC. Preliminary data indicate the superiority of PET/MRI for the detection of local recurrence in PC, local tumour invasion in cervical cancer, and liver metastases in colorectal cancer. These conclusions are based on small datasets and need to be further explored.

Identifiants

pubmed: 31267161
doi: 10.1007/s00259-019-04402-8
pii: 10.1007/s00259-019-04402-8
doi:

Substances chimiques

Gallium Isotopes 0
Gallium Radioisotopes 0
Oligopeptides 0
Radiopharmaceuticals 0
gallium 68 PSMA-11 0
Fluorodeoxyglucose F18 0Z5B2CJX4D
Edetic Acid 9G34HU7RV0

Types de publication

Journal Article Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

2138-2151

Références

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Auteurs

Anni Morsing (A)

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark. Anni.morsing@dadlnet.dk.
MAgNetic Resonance Technology for Response Adapted Radiotherapy (MANTRA), Odense University Hospital, Odense, Denmark. Anni.morsing@dadlnet.dk.

Malene Grubbe Hildebrandt (MG)

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Research Unit of Clinical Physiology and Nuclear Medicine, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Centre for Innovative Medical Technology (CIMT), Odense University Hospital, Odense, Denmark.

Mie Holm Vilstrup (MH)

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.

Sara Elisabeth Wallenius (SE)

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.

Oke Gerke (O)

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.

Henrik Petersen (H)

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.

Allan Johansen (A)

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.

Thomas Lund Andersen (TL)

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
MAgNetic Resonance Technology for Response Adapted Radiotherapy (MANTRA), Odense University Hospital, Odense, Denmark.

Poul Flemming Høilund-Carlsen (PF)

Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark.
Research Unit of Clinical Physiology and Nuclear Medicine, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

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